BRD-K71303366_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K71303366_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADGRG6 adhesion G protein-coupled receptor G6
AGTR1 angiotensin II receptor, type 1
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
C10ORF10 chromosome 10 open reading frame 10
CALR calreticulin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
CIRBP cold inducible RNA binding protein
CTGF connective tissue growth factor
CTSZ cathepsin Z
DHRS3 dehydrogenase/reductase (SDR family) member 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EXT1 exostosin glycosyltransferase 1
FADS1 fatty acid desaturase 1
FHL1 four and a half LIM domains 1
GDF15 growth differentiation factor 15
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSN gelsolin
HBB hemoglobin, beta
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LAPTM5 lysosomal protein transmembrane 5
LGALS1 lectin, galactoside-binding, soluble, 1
LIMCH1 LIM and calponin homology domains 1
MCAM melanoma cell adhesion molecule
MGLL monoglyceride lipase
NCF2 neutrophil cytosolic factor 2
PALLD palladin, cytoskeletal associated protein
PLIN2 perilipin 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100A4 S100 calcium binding protein A4
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
SYNM synemin, intermediate filament protein
TCTA T-cell leukemia translocation altered
TFRC transferrin receptor
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TP53I3 tumor protein p53 inducible protein 3
TPD52L1 tumor protein D52-like 1
TUBB2A tubulin, beta 2A class IIa
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AUTS2 autism susceptibility candidate 2
BLCAP bladder cancer associated protein
CA12 carbonic anhydrase XII
CCND2 cyclin D2
CETN2 centrin, EF-hand protein, 2
CHL1 cell adhesion molecule L1-like
COL5A2 collagen, type V, alpha 2
EDNRA endothelin receptor type A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAM57A family with sequence similarity 57, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
IFITM1 interferon induced transmembrane protein 1
IFT57 intraflagellar transport 57
MSRB1 methionine sulfoxide reductase B1
MTA1 metastasis associated 1
NRN1 neuritin 1
PLTP phospholipid transfer protein
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TCF4 transcription factor 4