BRD-K71670746_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K71670746_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BEX1 brain expressed, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
CHI3L2 chitinase 3-like 2
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
EFS embryonal Fyn-associated substrate
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FN1 fibronectin 1
FRY furry homolog (Drosophila)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
KCTD14 potassium channel tetramerization domain containing 14
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PER1 period circadian clock 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
WASF3 WAS protein family, member 3
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CDC42 cell division cycle 42
CLEC2B C-type lectin domain family 2, member B
DCN decorin
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
IL13RA2 interleukin 13 receptor, alpha 2
MUC16 mucin 16, cell surface associated
NR2F2 nuclear receptor subfamily 2, group F, member 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
RPS27L ribosomal protein S27-like
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TFPI2 tissue factor pathway inhibitor 2
TMEM30B transmembrane protein 30B
UFM1 ubiquitin-fold modifier 1
Funding