BRD-K72264770_-666_MCF7_6.0_h_10.0_um Gene Set
Genes
31 genes differentially expressed following the BRD-K72264770_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
ACSL1
|
acyl-CoA synthetase long-chain family member 1
|
BHLHE40
|
basic helix-loop-helix family, member e40
|
BNIP3
|
BCL2/adenovirus E1B 19kDa interacting protein 3
|
DAPK1
|
death-associated protein kinase 1
|
DDIT4
|
DNA-damage-inducible transcript 4
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
HK2
|
hexokinase 2
|
IRS2
|
insulin receptor substrate 2
|
KCNE4
|
potassium channel, voltage gated subfamily E regulatory beta subunit 4
|
KDM4B
|
lysine (K)-specific demethylase 4B
|
MET
|
MET proto-oncogene, receptor tyrosine kinase
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
NAMPT
|
nicotinamide phosphoribosyltransferase
|
PER1
|
period circadian clock 1
|
SEL1L3
|
sel-1 suppressor of lin-12-like 3 (C. elegans)
|
SLC1A1
|
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
|
SLC2A1
|
solute carrier family 2 (facilitated glucose transporter), member 1
|
TCF4
|
transcription factor 4
|
UCHL1
|
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
|
decreased expression
Symbol |
Name |
ADGRL2
|
adhesion G protein-coupled receptor L2
|
CANT1
|
calcium activated nucleotidase 1
|
CCL5
|
chemokine (C-C motif) ligand 5
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
ERBB4
|
erb-b2 receptor tyrosine kinase 4
|
HSPA1A
|
heat shock 70kDa protein 1A
|
LPAR6
|
lysophosphatidic acid receptor 6
|
PTGER4
|
prostaglandin E receptor 4 (subtype EP4)
|
TNFSF10
|
tumor necrosis factor (ligand) superfamily, member 10
|
TNNT1
|
troponin T type 1 (skeletal, slow)
|
TUSC3
|
tumor suppressor candidate 3
|
YWHAE
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
|