BRD-K72307842_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

114 genes differentially expressed following the BRD-K72307842_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACE2 angiotensin I converting enzyme 2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AMPD1 adenosine monophosphate deaminase 1
AQP3 aquaporin 3 (Gill blood group)
BBX bobby sox homolog (Drosophila)
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHGB chromogranin B
COL4A5 collagen, type IV, alpha 5
CXCL5 chemokine (C-X-C motif) ligand 5
EPAS1 endothelial PAS domain protein 1
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
FOLR1 folate receptor 1 (adult)
GCG glucagon
GSTA1 glutathione S-transferase alpha 1
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFITM1 interferon induced transmembrane protein 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JCHAIN joining chain of multimeric IgA and IgM
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT13 keratin 13, type I
KRT6A keratin 6A, type II
MALL mal, T-cell differentiation protein-like
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MPO myeloperoxidase
MT1E metallothionein 1E
MT1F metallothionein 1F
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NTS neurotensin
PALMD palmdelphin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFA platelet-derived growth factor alpha polypeptide
PLAU plasminogen activator, urokinase
PRKCH protein kinase C, eta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
S100A2 S100 calcium binding protein A2
SCEL sciellin
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TACSTD2 tumor-associated calcium signal transducer 2
TMEM47 transmembrane protein 47
TNNC1 troponin C type 1 (slow)
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRPS1 trichorhinophalangeal syndrome I
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UPK1B uroplakin 1B
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ANXA4 annexin A4
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASRGL1 asparaginase like 1
ATF5 activating transcription factor 5
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CANT1 calcium activated nucleotidase 1
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPNE1 copine I
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPYSL2 dihydropyrimidinase-like 2
DUSP6 dual specificity phosphatase 6
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
FAM60A family with sequence similarity 60, member A
GSDMB gasdermin B
HOXB7 homeobox B7
HSPA1A heat shock 70kDa protein 1A
KDM5D lysine (K)-specific demethylase 5D
LY6E lymphocyte antigen 6 complex, locus E
MGLL monoglyceride lipase
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PHB prohibitin
PHLDA2 pleckstrin homology-like domain, family A, member 2
PSIP1 PC4 and SFRS1 interacting protein 1
PWP1 PWP1 homolog (S. cerevisiae)
RECQL RecQ helicase-like
RND3 Rho family GTPase 3
RNH1 ribonuclease/angiogenin inhibitor 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAND1 SCAN domain containing 1
SCGB1D2 secretoglobin, family 1D, member 2
SNX10 sorting nexin 10
SOX11 SRY (sex determining region Y)-box 11
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPRED2 sprouty-related, EVH1 domain containing 2
TMSB15A thymosin beta 15a
TRIB3 tribbles pseudokinase 3
WDR61 WD repeat domain 61