| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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137 genes differentially expressed following the BRD-K72414522_AZD-5438_HME1_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ACKR3 | atypical chemokine receptor 3 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASS1 | argininosuccinate synthase 1 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BMP2 | bone morphogenetic protein 2 |
| C3 | complement component 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CFB | complement factor B |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CLU | clusterin |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DPT | dermatopontin |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| EPCAM | epithelial cell adhesion molecule |
| FHL1 | four and a half LIM domains 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| HK2 | hexokinase 2 |
| HOOK2 | hook microtubule-tethering protein 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MT1M | metallothionein 1M |
| MXRA5 | matrix-remodelling associated 5 |
| NAAA | N-acylethanolamine acid amidase |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NID2 | nidogen 2 (osteonidogen) |
| NRIP1 | nuclear receptor interacting protein 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PPIF | peptidylprolyl isomerase F |
| PRDX2 | peroxiredoxin 2 |
| PRKCQ | protein kinase C, theta |
| PSPH | phosphoserine phosphatase |
| PTK2B | protein tyrosine kinase 2 beta |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBP1 | retinol binding protein 1, cellular |
| RNF144A | ring finger protein 144A |
| SCG5 | secretogranin V |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFN | stratifin |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| STMN2 | stathmin 2 |
| TGFA | transforming growth factor, alpha |
| TMEM176B | transmembrane protein 176B |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPD52 | tumor protein D52 |
| TSPAN7 | tetraspanin 7 |
| XIST | X inactive specific transcript (non-protein coding) |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AUTS2 | autism susceptibility candidate 2 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CAV2 | caveolin 2 |
| CCNA2 | cyclin A2 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| ETV1 | ets variant 1 |
| FADS2 | fatty acid desaturase 2 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| FZD7 | frizzled class receptor 7 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXB2 | homeobox B2 |
| HOXB7 | homeobox B7 |
| HOXC6 | homeobox C6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JADE2 | jade family PHD finger 2 |
| KIF20A | kinesin family member 20A |
| LDLR | low density lipoprotein receptor |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MMP1 | matrix metallopeptidase 1 |
| MSMO1 | methylsterol monooxygenase 1 |
| NDC80 | NDC80 kinetochore complex component |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFD | platelet derived growth factor D |
| PLK1 | polo-like kinase 1 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PUF60 | poly-U binding splicing factor 60KDa |
| PXDN | peroxidasin |
| PYGB | phosphorylase, glycogen; brain |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS2 | regulator of G-protein signaling 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SC5D | sterol-C5-desaturase |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC38A2 | solute carrier family 38, member 2 |
| SMAGP | small cell adhesion glycoprotein |
| SMC4 | structural maintenance of chromosomes 4 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| STMN1 | stathmin 1 |
| STOM | stomatin |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM50A | transmembrane protein 50A |
| TTK | TTK protein kinase |
| TUBA1A | tubulin, alpha 1a |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
