| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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245 genes differentially expressed following the BRD-K72414522_AZD-5438_HME1_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACKR3 | atypical chemokine receptor 3 |
| ACP5 | acid phosphatase 5, tartrate resistant |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AQP8 | aquaporin 8 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| AZIN1 | antizyme inhibitor 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| C8ORF33 | chromosome 8 open reading frame 33 |
| CA11 | carbonic anhydrase XI |
| CALB1 | calbindin 1, 28kDa |
| CCDC47 | coiled-coil domain containing 47 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD300A | CD300a molecule |
| CELF2 | CUGBP, Elav-like family member 2 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CLCA4 | chloride channel accessory 4 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| DOK5 | docking protein 5 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| F12 | coagulation factor XII (Hageman factor) |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| GATAD2A | GATA zinc finger domain containing 2A |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GLS | glutaminase |
| GOLT1B | golgi transport 1B |
| GPR183 | G protein-coupled receptor 183 |
| HDAC9 | histone deacetylase 9 |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IER5 | immediate early response 5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| JAG1 | jagged 1 |
| KCMF1 | potassium channel modulatory factor 1 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT13 | keratin 13, type I |
| KRT19 | keratin 19, type I |
| KRT4 | keratin 4, type II |
| KRT6A | keratin 6A, type II |
| LOC283683 | uncharacterized LOC283683 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MLF1 | myeloid leukemia factor 1 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| MUC16 | mucin 16, cell surface associated |
| MXI1 | MAX interactor 1, dimerization protein |
| MXRA5 | matrix-remodelling associated 5 |
| NDP | Norrie disease (pseudoglioma) |
| NGRN | neugrin, neurite outgrowth associated |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PER2 | period circadian clock 2 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHF20 | PHD finger protein 20 |
| PLIN2 | perilipin 2 |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa |
| PRR7 | proline rich 7 (synaptic) |
| PTDSS1 | phosphatidylserine synthase 1 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RBM15 | RNA binding motif protein 15 |
| RBP1 | retinol binding protein 1, cellular |
| REG1A | regenerating islet-derived 1 alpha |
| RIOK3 | RIO kinase 3 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPS5 | ribosomal protein S5 |
| RRAD | Ras-related associated with diabetes |
| RRAGD | Ras-related GTP binding D |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RUNX3 | runt-related transcription factor 3 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SATB2 | SATB homeobox 2 |
| SCG5 | secretogranin V |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERTAD2 | SERTA domain containing 2 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SMAD7 | SMAD family member 7 |
| SMIM7 | small integral membrane protein 7 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRR2B | small proline-rich protein 2B |
| SST | somatostatin |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
| TGFA | transforming growth factor, alpha |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) |
| TPD52 | tumor protein D52 |
| TSPAN7 | tetraspanin 7 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WDR3 | WD repeat domain 3 |
| WDR45B | WD repeat domain 45B |
| WT1 | Wilms tumor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| ZNF331 | zinc finger protein 331 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGR2 | anterior gradient 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATF5 | activating transcription factor 5 |
| AURKA | aurora kinase A |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CAST | calpastatin |
| CAV2 | caveolin 2 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCNG2 | cyclin G2 |
| CDC20 | cell division cycle 20 |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CENPF | centromere protein F, 350/400kDa |
| CFH | complement factor H |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL5A2 | collagen, type V, alpha 2 |
| CTGF | connective tissue growth factor |
| DCN | decorin |
| DEPDC1 | DEP domain containing 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DMD | dystrophin |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM129A | family with sequence similarity 129, member A |
| FBN1 | fibrillin 1 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FOXM1 | forkhead box M1 |
| FZD7 | frizzled class receptor 7 |
| GAS1 | growth arrest-specific 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GTSE1 | G-2 and S-phase expressed 1 |
| HMGB2 | high mobility group box 2 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXC6 | homeobox C6 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGHM | immunoglobulin heavy constant mu |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JADE2 | jade family PHD finger 2 |
| KIF14 | kinesin family member 14 |
| KIF1BP | KIF1 binding protein |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIF2C | kinesin family member 2C |
| KIF4A | kinesin family member 4A |
| LAMB1 | laminin, beta 1 |
| LBR | lamin B receptor |
| LIMA1 | LIM domain and actin binding 1 |
| LOX | lysyl oxidase |
| LOXL2 | lysyl oxidase-like 2 |
| LUM | lumican |
| LXN | latexin |
| MAGED1 | melanoma antigen family D1 |
| MAGED2 | melanoma antigen family D2 |
| MANSC1 | MANSC domain containing 1 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MCM5 | minichromosome maintenance complex component 5 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MKI67 | marker of proliferation Ki-67 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NDC80 | NDC80 kinetochore complex component |
| NEK7 | NIMA-related kinase 7 |
| NMI | N-myc (and STAT) interactor |
| NNMT | nicotinamide N-methyltransferase |
| NRP1 | neuropilin 1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OSBPL8 | oxysterol binding protein-like 8 |
| PBK | PDZ binding kinase |
| PCM1 | pericentriolar material 1 |
| PLK1 | polo-like kinase 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRSS23 | protease, serine, 23 |
| PXDN | peroxidasin |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBPMS | RNA binding protein with multiple splicing |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SFRP1 | secreted frizzled-related protein 1 |
| SMC2 | structural maintenance of chromosomes 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| STMN1 | stathmin 1 |
| STOM | stomatin |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TESC | tescalcin |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMEM50A | transmembrane protein 50A |
| TMSB15A | thymosin beta 15a |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPM1 | tropomyosin 1 (alpha) |
| TPX2 | TPX2, microtubule-associated |
| TSPAN13 | tetraspanin 13 |
| TSPAN8 | tetraspanin 8 |
| TTK | TTK protein kinase |
| TXNIP | thioredoxin interacting protein |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VCAN | versican |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
