BRD-K72420232_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

18 genes differentially expressed following the BRD-K72420232_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CPT1A carnitine palmitoyltransferase 1A (liver)
DDIT4 DNA-damage-inducible transcript 4
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FHL1 four and a half LIM domains 1
GRB10 growth factor receptor-bound protein 10
HAPLN1 hyaluronan and proteoglycan link protein 1
HMOX1 heme oxygenase 1
MYLK myosin light chain kinase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG3 paternally expressed 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CKAP4 cytoskeleton-associated protein 4
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
RND3 Rho family GTPase 3