Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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59 genes differentially expressed following the BRD-K72420232_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD4 | abhydrolase domain containing 4 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C3 | aldo-keto reductase family 1, member C3 |
APOD | apolipoprotein D |
ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
ARMCX1 | armadillo repeat containing, X-linked 1 |
CD163 | CD163 molecule |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
CLCA2 | chloride channel accessory 2 |
DDIT4 | DNA-damage-inducible transcript 4 |
DEPTOR | DEP domain containing MTOR-interacting protein |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
EMX2 | empty spiracles homeobox 2 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
FGFR1 | fibroblast growth factor receptor 1 |
GAA | glucosidase, alpha; acid |
GRB14 | growth factor receptor-bound protein 14 |
GRN | granulin |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
IGF1R | insulin-like growth factor 1 receptor |
KRT6A | keratin 6A, type II |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MFAP5 | microfibrillar associated protein 5 |
MYO10 | myosin X |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
RAB38 | RAB38, member RAS oncogene family |
RBP1 | retinol binding protein 1, cellular |
TBL1X | transducin (beta)-like 1X-linked |
THBD | thrombomodulin |
TP53 | tumor protein p53 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADD3 | adducin 3 (gamma) |
ANXA1 | annexin A1 |
CADM1 | cell adhesion molecule 1 |
CD24 | CD24 molecule |
COX11 | COX11 cytochrome c oxidase copper chaperone |
DPYSL3 | dihydropyrimidinase-like 3 |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
IER3 | immediate early response 3 |
KRT18 | keratin 18, type I |
KRT19 | keratin 19, type I |
LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MMP9 | matrix metallopeptidase 9 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
ODC1 | ornithine decarboxylase 1 |
PNP | purine nucleoside phosphorylase |
RBP4 | retinol binding protein 4, plasma |
RRM2 | ribonucleotide reductase M2 |
S100A10 | S100 calcium binding protein A10 |
SOX4 | SRY (sex determining region Y)-box 4 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TFRC | transferrin receptor |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |