BRD-K72615639_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K72615639_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
FHL1 four and a half LIM domains 1
GOLGA8A golgin A8 family, member A
GPI glucose-6-phosphate isomerase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LOX lysyl oxidase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MFAP5 microfibrillar associated protein 5
NANOG Nanog homeobox
NID2 nidogen 2 (osteonidogen)
NPTX2 neuronal pentraxin II
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PELI1 pellino E3 ubiquitin protein ligase 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
RGS5 regulator of G-protein signaling 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
VEGFA vascular endothelial growth factor A
VIM vimentin
VLDLR very low density lipoprotein receptor
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AURKA aurora kinase A
CCL19 chemokine (C-C motif) ligand 19
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CXCL13 chemokine (C-X-C motif) ligand 13
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
GATA3 GATA binding protein 3
GPSM2 G-protein signaling modulator 2
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KRT10 keratin 10, type I
MMP7 matrix metallopeptidase 7
PLK1 polo-like kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S