BRD-K72636697_QL-X-138_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K72636697_QL-X-138_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
AXL AXL receptor tyrosine kinase
BHLHE41 basic helix-loop-helix family, member e41
CD44 CD44 molecule (Indian blood group)
CLIC5 chloride intracellular channel 5
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DOK5 docking protein 5
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FGF13 fibroblast growth factor 13
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
GPX3 glutathione peroxidase 3
HOXC6 homeobox C6
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITM2A integral membrane protein 2A
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP2K5 mitogen-activated protein kinase kinase 5
MEF2C myocyte enhancer factor 2C
MSN moesin
MYBPC1 myosin binding protein C, slow type
MYOF myoferlin
MYOT myotilin
NPTX2 neuronal pentraxin II
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PADI2 peptidyl arginine deiminase, type II
PDGFC platelet derived growth factor C
PEX11A peroxisomal biogenesis factor 11 alpha
PLCB4 phospholipase C, beta 4
PROM1 prominin 1
SCGB1D2 secretoglobin, family 1D, member 2
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFTPA2 surfactant protein A2
SLPI secretory leukocyte peptidase inhibitor
SYBU syntabulin (syntaxin-interacting)
SYNM synemin, intermediate filament protein
TGFA transforming growth factor, alpha
TMEM47 transmembrane protein 47
TNNC2 troponin C type 2 (fast)
TNNT1 troponin T type 1 (skeletal, slow)
TOX thymocyte selection-associated high mobility group box
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
TSPAN31 tetraspanin 31
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
VIM vimentin
WWTR1 WW domain containing transcription regulator 1
ZEB2 zinc finger E-box binding homeobox 2

decreased expression

Symbol Name
ADM adrenomedullin
CA2 carbonic anhydrase II
CALML5 calmodulin-like 5
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDC42 cell division cycle 42
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL6A3 collagen, type VI, alpha 3
CTSK cathepsin K
CXCL9 chemokine (C-X-C motif) ligand 9
DNM1L dynamin 1-like
FASN fatty acid synthase
HIC2 hypermethylated in cancer 2
IDO1 indoleamine 2,3-dioxygenase 1
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
MMD monocyte to macrophage differentiation-associated
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PF4 platelet factor 4
PLBD1 phospholipase B domain containing 1
PMM2 phosphomannomutase 2
RAD23B RAD23 homolog B (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SOD2 superoxide dismutase 2, mitochondrial
STAT1 signal transducer and activator of transcription 1, 91kDa
TFRC transferrin receptor
TJP2 tight junction protein 2
TUBB2A tubulin, beta 2A class IIa
VWF von Willebrand factor
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
Funding