| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
165 genes differentially expressed following the BRD-K72636697_QL-X-138_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ATM | ATM serine/threonine kinase |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BTG2 | BTG family, member 2 |
| CADM1 | cell adhesion molecule 1 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CYTH1 | cytohesin 1 |
| DCN | decorin |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DSG2 | desmoglein 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ESR1 | estrogen receptor 1 |
| EXPH5 | exophilin 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBLN1 | fibulin 1 |
| FOXO3 | forkhead box O3 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| FZD7 | frizzled class receptor 7 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IRF7 | interferon regulatory factor 7 |
| IRS1 | insulin receptor substrate 1 |
| KAT6B | K(lysine) acetyltransferase 6B |
| KIAA1324 | KIAA1324 |
| KIZ | kizuna centrosomal protein |
| KRT19 | keratin 19, type I |
| KRT23 | keratin 23, type I |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC100272216 | uncharacterized LOC100272216 |
| LRRC17 | leucine rich repeat containing 17 |
| LXN | latexin |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MEIS1 | Meis homeobox 1 |
| MLPH | melanophilin |
| MSLN | mesothelin |
| MTSS1 | metastasis suppressor 1 |
| MUC16 | mucin 16, cell surface associated |
| MVP | major vault protein |
| MXRA5 | matrix-remodelling associated 5 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NEFH | neurofilament, heavy polypeptide |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PDGFC | platelet derived growth factor C |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLCB4 | phospholipase C, beta 4 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| PSPH | phosphoserine phosphatase |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RGS10 | regulator of G-protein signaling 10 |
| RTN2 | reticulon 2 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SECISBP2L | SECIS binding protein 2-like |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SVIL | supervillin |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TJP2 | tight junction protein 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TXNIP | thioredoxin interacting protein |
| URI1 | URI1, prefoldin-like chaperone |
| USP34 | ubiquitin specific peptidase 34 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| Symbol | Name |
|---|---|
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CA2 | carbonic anhydrase II |
| CALR | calreticulin |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CCND3 | cyclin D3 |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK1 | cyclin-dependent kinase 1 |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| COL1A2 | collagen, type I, alpha 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYCS | cytochrome c, somatic |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCK | deoxycytidine kinase |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| EBP | emopamil binding protein (sterol isomerase) |
| EDNRB | endothelin receptor type B |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FASN | fatty acid synthase |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOXG1 | forkhead box G1 |
| GAL | galanin/GMAP prepropeptide |
| GNAS | GNAS complex locus |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GOLT1B | golgi transport 1B |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HIST1H4C | histone cluster 1, H4c |
| HSPA14 | heat shock 70kDa protein 14 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IFRD2 | interferon-related developmental regulator 2 |
| IL1RN | interleukin 1 receptor antagonist |
| KRT5 | keratin 5, type II |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LRRC59 | leucine rich repeat containing 59 |
| MAL | mal, T-cell differentiation protein |
| MALT1 | MALT1 paracaspase |
| MCM4 | minichromosome maintenance complex component 4 |
| MELK | maternal embryonic leucine zipper kinase |
| MGP | matrix Gla protein |
| MMP12 | matrix metallopeptidase 12 |
| MMP3 | matrix metallopeptidase 3 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NFIB | nuclear factor I/B |
| PCDH17 | protocadherin 17 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLAC8 | placenta-specific 8 |
| PLK1 | polo-like kinase 1 |
| POSTN | periostin, osteoblast specific factor |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RRM2 | ribonucleotide reductase M2 |
| S100A7 | S100 calcium binding protein A7 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC35B1 | solute carrier family 35, member B1 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| TMEM47 | transmembrane protein 47 |
| TNC | tenascin C |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB2A | tubulin, beta 2A class IIa |
| TYMS | thymidylate synthetase |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZWINT | ZW10 interacting kinetochore protein |
