BRD-K72636697_QL-X-138_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K72636697_QL-X-138_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BTG1 B-cell translocation gene 1, anti-proliferative
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHN1 chimerin 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
EIF5A eukaryotic translation initiation factor 5A
ELF1 E74-like factor 1 (ets domain transcription factor)
EPAS1 endothelial PAS domain protein 1
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FAM57A family with sequence similarity 57, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
FXYD3 FXYD domain containing ion transport regulator 3
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD10 frizzled class receptor 10
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRB7 growth factor receptor-bound protein 7
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BD histone cluster 1, H2bd
IFITM1 interferon induced transmembrane protein 1
KIAA0355 KIAA0355
LGALS3 lectin, galactoside-binding, soluble, 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MBNL2 muscleblind-like splicing regulator 2
MGLL monoglyceride lipase
N4BP2L2 NEDD4 binding protein 2-like 2
NOTCH2NL notch 2 N-terminal like
NPIPB3 nuclear pore complex interacting protein family, member B3
OAT ornithine aminotransferase
PTN pleiotrophin
S100P S100 calcium binding protein P
TIMP1 TIMP metallopeptidase inhibitor 1
TLK2 tousled-like kinase 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8
WEE1 WEE1 G2 checkpoint kinase

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
CDC25A cell division cycle 25A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRZB frizzled-related protein
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
PDHX pyruvate dehydrogenase complex, component X
PRSS2 protease, serine, 2 (trypsin 2)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
Funding