Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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110 genes differentially expressed following the BRD-K72703948_ZM-447439_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADD3 | adducin 3 (gamma) |
AQP3 | aquaporin 3 (Gill blood group) |
ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CAST | calpastatin |
CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
CECR1 | cat eye syndrome chromosome region, candidate 1 |
CHN1 | chimerin 1 |
CKLF | chemokine-like factor |
CPB1 | carboxypeptidase B1 (tissue) |
CRABP2 | cellular retinoic acid binding protein 2 |
CTSS | cathepsin S |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
ECI2 | enoyl-CoA delta isomerase 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
GAGE3 | G antigen 3 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
H2BFS | H2B histone family, member S (pseudogene) |
HEATR1 | HEAT repeat containing 1 |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BK | histone cluster 1, H2bk |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
IDO1 | indoleamine 2,3-dioxygenase 1 |
KIF14 | kinesin family member 14 |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
LRRC8D | leucine rich repeat containing 8 family, member D |
LY75 | lymphocyte antigen 75 |
MAGEA12 | melanoma antigen family A12 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MAL | mal, T-cell differentiation protein |
MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
METTL7A | methyltransferase like 7A |
MMP1 | matrix metallopeptidase 1 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
NOV | nephroblastoma overexpressed |
NRN1 | neuritin 1 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PEG10 | paternally expressed 10 |
PPAP2B | phosphatidic acid phosphatase type 2B |
PRSS21 | protease, serine, 21 (testisin) |
PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) |
RABGGTB | Rab geranylgeranyltransferase, beta subunit |
RGCC | regulator of cell cycle |
RPL31 | ribosomal protein L31 |
SELENBP1 | selenium binding protein 1 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
SPRED2 | sprouty-related, EVH1 domain containing 2 |
TOP1 | topoisomerase (DNA) I |
TUSC3 | tumor suppressor candidate 3 |
UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Symbol | Name |
---|---|
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
BZW2 | basic leucine zipper and W2 domains 2 |
CADM1 | cell adhesion molecule 1 |
CD69 | CD69 molecule |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CENPE | centromere protein E, 312kDa |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
DCN | decorin |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DLK1 | delta-like 1 homolog (Drosophila) |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
EIF5A | eukaryotic translation initiation factor 5A |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
FHL1 | four and a half LIM domains 1 |
FILIP1L | filamin A interacting protein 1-like |
FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
HBB | hemoglobin, beta |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
IGHM | immunoglobulin heavy constant mu |
IL32 | interleukin 32 |
ISG15 | ISG15 ubiquitin-like modifier |
KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
KRT13 | keratin 13, type I |
KRT19 | keratin 19, type I |
LTF | lactotransferrin |
LUM | lumican |
MET | MET proto-oncogene, receptor tyrosine kinase |
MX1 | MX dynamin-like GTPase 1 |
MYBPC1 | myosin binding protein C, slow type |
NEBL | nebulette |
P3H2 | prolyl 3-hydroxylase 2 |
PAPD7 | PAP associated domain containing 7 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PRPF4 | pre-mRNA processing factor 4 |
RAD51C | RAD51 paralog C |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
RTN2 | reticulon 2 |
S100A8 | S100 calcium binding protein A8 |
S100P | S100 calcium binding protein P |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
SLC38A1 | solute carrier family 38, member 1 |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
STOM | stomatin |
SYNE1 | spectrin repeat containing, nuclear envelope 1 |
TFF3 | trefoil factor 3 (intestinal) |
TLE4 | transducin-like enhancer of split 4 |
TSPYL5 | TSPY-like 5 |
VCAM1 | vascular cell adhesion molecule 1 |