BRD-K72723676_Benzethonium chloride_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K72723676_Benzethonium chloride_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BICC1 BicC family RNA binding protein 1
CADM1 cell adhesion molecule 1
COL15A1 collagen, type XV, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DPP4 dipeptidyl-peptidase 4
F12 coagulation factor XII (Hageman factor)
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIAA1033 KIAA1033
KRT15 keratin 15, type I
KRT5 keratin 5, type II
MSMO1 methylsterol monooxygenase 1
NNT nicotinamide nucleotide transhydrogenase
NPC2 Niemann-Pick disease, type C2
PLXNC1 plexin C1
PRR7 proline rich 7 (synaptic)
RCAN1 regulator of calcineurin 1
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SDC2 syndecan 2
SLC22A18 solute carrier family 22, member 18
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TATDN2 TatD DNase domain containing 2
THBS2 thrombospondin 2
TIMP2 TIMP metallopeptidase inhibitor 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSC22D3 TSC22 domain family, member 3
TXN thioredoxin
TXNIP thioredoxin interacting protein
VCAN versican

decreased expression

Symbol Name
AVPI1 arginine vasopressin-induced 1
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL13 chemokine (C-X-C motif) ligand 13
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLX2 distal-less homeobox 2
FABP4 fatty acid binding protein 4, adipocyte
FGFR2 fibroblast growth factor receptor 2
GHR growth hormone receptor
HBEGF heparin-binding EGF-like growth factor
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
JAG1 jagged 1
JMJD6 jumonji domain containing 6
JUP junction plakoglobin
MSLN mesothelin
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR2F6 nuclear receptor subfamily 2, group F, member 6
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUVBL1 RuvB-like AAA ATPase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SKP1 S-phase kinase-associated protein 1
SRGN serglycin
STAB1 stabilin 1
XIST X inactive specific transcript (non-protein coding)