BRD-K73290745_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K73290745_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CSTA cystatin A (stefin A)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLK1 delta-like 1 homolog (Drosophila)
FBN2 fibrillin 2
HSPA2 heat shock 70kDa protein 2
IPO13 importin 13
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT14 keratin 14, type I
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP1 latent transforming growth factor beta binding protein 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
SHB Src homology 2 domain containing adaptor protein B
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SQLE squalene epoxidase
TNS3 tensin 3
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CAST calpastatin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42 cell division cycle 42
CLCA4 chloride channel accessory 4
FAIM Fas apoptotic inhibitory molecule
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
KLF6 Kruppel-like factor 6
LXN latexin
MDFIC MyoD family inhibitor domain containing
NNMT nicotinamide N-methyltransferase
PSPH phosphoserine phosphatase
SOAT1 sterol O-acyltransferase 1
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TM4SF1 transmembrane 4 L six family member 1
UGCG UDP-glucose ceramide glucosyltransferase