BRD-K73290745_-666_HT29_6.0_h_10.0_um Gene Set
Genes
29 genes differentially expressed following the BRD-K73290745_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
ADH1B
|
alcohol dehydrogenase 1B (class I), beta polypeptide
|
|
CST1
|
cystatin SN
|
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
|
DHCR7
|
7-dehydrocholesterol reductase
|
|
FADS1
|
fatty acid desaturase 1
|
|
FASN
|
fatty acid synthase
|
|
FDPS
|
farnesyl diphosphate synthase
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
|
INSIG1
|
insulin induced gene 1
|
|
IPO13
|
importin 13
|
|
LDLR
|
low density lipoprotein receptor
|
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
|
MAP7
|
microtubule-associated protein 7
|
|
MSMO1
|
methylsterol monooxygenase 1
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
SQLE
|
squalene epoxidase
|
|
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
decreased expression
| Symbol |
Name |
|
CD24
|
CD24 molecule
|
|
GCH1
|
GTP cyclohydrolase 1
|
|
HBEGF
|
heparin-binding EGF-like growth factor
|
|
LYZ
|
lysozyme
|
|
MMP9
|
matrix metallopeptidase 9
|
|
NSF
|
N-ethylmaleimide-sensitive factor
|
|
ODC1
|
ornithine decarboxylase 1
|
|
RGS2
|
regulator of G-protein signaling 2
|
