BRD-K73315009_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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73 genes differentially expressed following the BRD-K73315009_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BCHE butyrylcholinesterase
CA1 carbonic anhydrase I
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CKB creatine kinase, brain
CLU clusterin
CRIP2 cysteine-rich protein 2
CRNN cornulin
DEFB1 defensin, beta 1
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
EGFR epidermal growth factor receptor
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ESR1 estrogen receptor 1
GBP1 guanylate binding protein 1, interferon-inducible
HOOK2 hook microtubule-tethering protein 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT5 keratin 5, type II
LOC100505650 uncharacterized LOC100505650
LRRC17 leucine rich repeat containing 17
MAMLD1 mastermind-like domain containing 1
MTA1 metastasis associated 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAGL1 pleiomorphic adenoma gene-like 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RNF167 ring finger protein 167
S100A7 S100 calcium binding protein A7
SATB2 SATB homeobox 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCTA T-cell leukemia translocation altered
TENM4 teneurin transmembrane protein 4
TKTL1 transketolase-like 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPR translocated promoter region, nuclear basket protein
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TSPAN13 tetraspanin 13
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ALCAM activated leukocyte cell adhesion molecule
APOD apolipoprotein D
BIRC3 baculoviral IAP repeat containing 3
CHN2 chimerin 2
COL2A1 collagen, type II, alpha 1
CTSK cathepsin K
DLK1 delta-like 1 homolog (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
FOLR1 folate receptor 1 (adult)
GPC3 glypican 3
HSPA8 heat shock 70kDa protein 8
IL1R2 interleukin 1 receptor, type II
ITM2A integral membrane protein 2A
LAMC2 laminin, gamma 2
MDK midkine (neurite growth-promoting factor 2)
MME membrane metallo-endopeptidase
MUC4 mucin 4, cell surface associated
NRN1 neuritin 1
RAB31 RAB31, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RELN reelin
S100P S100 calcium binding protein P
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPP1 secreted phosphoprotein 1
SRGN serglycin
STS steroid sulfatase (microsomal), isozyme S
THBS2 thrombospondin 2
TSPAN8 tetraspanin 8