BRD-K73945663_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K73945663_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANXA1 annexin A1
CCNA1 cyclin A1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIRBP cold inducible RNA binding protein
CLIC4 chloride intracellular channel 4
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DPYSL3 dihydropyrimidinase-like 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FXYD6 FXYD domain containing ion transport regulator 6
GDF15 growth differentiation factor 15
IGFBP5 insulin-like growth factor binding protein 5
KRT7 keratin 7, type II
LGALS1 lectin, galactoside-binding, soluble, 1
MGP matrix Gla protein
MYH11 myosin, heavy chain 11, smooth muscle
NFIB nuclear factor I/B
PLCB4 phospholipase C, beta 4
PRAME preferentially expressed antigen in melanoma
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TGM2 transglutaminase 2
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CALD1 caldesmon 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND1 cyclin D1
CHD7 chromodomain helicase DNA binding protein 7
CXCL14 chemokine (C-X-C motif) ligand 14
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MARCKS myristoylated alanine-rich protein kinase C substrate
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PTX3 pentraxin 3, long
SLK STE20-like kinase
TXNIP thioredoxin interacting protein
ZNF91 zinc finger protein 91
Funding