BRD-K73945663_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K73945663_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ANPEP alanyl (membrane) aminopeptidase
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CHRDL1 chordin-like 1
CSTA cystatin A (stefin A)
DHCR24 24-dehydrocholesterol reductase
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GSTA1 glutathione S-transferase alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
KRT14 keratin 14, type I
LDLR low density lipoprotein receptor
LPIN1 lipin 1
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
PAX5 paired box 5
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDLIM4 PDZ and LIM domain 4
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPRE protein tyrosine phosphatase, receptor type, E
RHOB ras homolog family member B
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQLE squalene epoxidase
TM4SF1 transmembrane 4 L six family member 1
TRIB2 tribbles pseudokinase 2
TRPS1 trichorhinophalangeal syndrome I
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
GADD45B growth arrest and DNA-damage-inducible, beta
HOXA10 homeobox A10
Funding