BRD-K74623475_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

66 genes differentially expressed following the BRD-K74623475_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOR2 adiponectin receptor 2
BHLHE40 basic helix-loop-helix family, member e40
CRABP2 cellular retinoic acid binding protein 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ELOVL5 ELOVL fatty acid elongase 5
EMP3 epithelial membrane protein 3
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM129A family with sequence similarity 129, member A
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
GPC3 glypican 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IER3 immediate early response 3
IGL immunoglobulin lambda locus
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
KLK10 kallikrein-related peptidase 10
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTF lactotransferrin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
MZB1 marginal zone B and B1 cell-specific protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NTS neurotensin
PANK3 pantothenate kinase 3
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
TIMP1 TIMP metallopeptidase inhibitor 1
TPBG trophoblast glycoprotein
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
VCAN versican
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CA2 carbonic anhydrase II
CBX3 chromobox homolog 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
FGFR3 fibroblast growth factor receptor 3
HSPA1A heat shock 70kDa protein 1A
SEPP1 selenoprotein P, plasma, 1