| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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163 genes differentially expressed following the BRD-K74690444_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACPP | acid phosphatase, prostate |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATF3 | activating transcription factor 3 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CD151 | CD151 molecule (Raph blood group) |
| CD9 | CD9 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CLDN3 | claudin 3 |
| CLDN4 | claudin 4 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EMP1 | epithelial membrane protein 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM60A | family with sequence similarity 60, member A |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| FOXG1 | forkhead box G1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HBP1 | HMG-box transcription factor 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXB2 | homeobox B2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| JUNB | jun B proto-oncogene |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MME | membrane metallo-endopeptidase |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1X | metallothionein 1X |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| RGCC | regulator of cell cycle |
| RGS1 | regulator of G-protein signaling 1 |
| RGS16 | regulator of G-protein signaling 16 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SMAD3 | SMAD family member 3 |
| SULF1 | sulfatase 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCF4 | transcription factor 4 |
| TGFB2 | transforming growth factor, beta 2 |
| TGM4 | transglutaminase 4 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| VEGFA | vascular endothelial growth factor A |
| YBX3 | Y box binding protein 3 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADD3 | adducin 3 (gamma) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ASXL2 | additional sex combs like transcriptional regulator 2 |
| AURKA | aurora kinase A |
| BRCA1 | breast cancer 1, early onset |
| C1S | complement component 1, s subcomponent |
| C6ORF62 | chromosome 6 open reading frame 62 |
| C7 | complement component 7 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CCNF | cyclin F |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DCN | decorin |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EIF5A | eukaryotic translation initiation factor 5A |
| FAM13B | family with sequence similarity 13, member B |
| FAM178A | family with sequence similarity 178, member A |
| FAM46A | family with sequence similarity 46, member A |
| FBXO9 | F-box protein 9 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GAS1 | growth arrest-specific 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GOLGA8A | golgin A8 family, member A |
| GPX2 | glutathione peroxidase 2 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HLTF | helicase-like transcription factor |
| HOXC6 | homeobox C6 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA8 | heat shock 70kDa protein 8 |
| IFI44 | interferon-induced protein 44 |
| ITM2A | integral membrane protein 2A |
| KIAA0907 | KIAA0907 |
| KIF14 | kinesin family member 14 |
| KIF18B | kinesin family member 18B |
| KYNU | kynureninase |
| LRRC16A | leucine rich repeat containing 16A |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP7 | microtubule-associated protein 7 |
| MFAP5 | microfibrillar associated protein 5 |
| MKKS | McKusick-Kaufman syndrome |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OLFM1 | olfactomedin 1 |
| OLFML1 | olfactomedin-like 1 |
| PLK1 | polo-like kinase 1 |
| PLXNC1 | plexin C1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| QPRT | quinolinate phosphoribosyltransferase |
| RAP2A | RAP2A, member of RAS oncogene family |
| RPIA | ribose 5-phosphate isomerase A |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAR1A | secretion associated, Ras related GTPase 1A |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFRC | transferrin receptor |
| TMEM47 | transmembrane protein 47 |
| TMEM97 | transmembrane protein 97 |
| TOB1 | transducer of ERBB2, 1 |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TSPAN13 | tetraspanin 13 |
| TSPAN8 | tetraspanin 8 |
| TSPYL5 | TSPY-like 5 |
