BRD-K74797618_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K74797618_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
BGN biglycan
COL10A1 collagen, type X, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
H2BFS H2B histone family, member S (pseudogene)
H3F3B H3 histone, family 3B (H3.3B)
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HIST1H2BK histone cluster 1, H2bk
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INHBA inhibin, beta A
IRF1 interferon regulatory factor 1
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KRT23 keratin 23, type I
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PERP PERP, TP53 apoptosis effector
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RGS16 regulator of G-protein signaling 16
RHOB ras homolog family member B
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STC1 stanniocalcin 1
TMSB15A thymosin beta 15a
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP13A3 ATPase type 13A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B3GNT1
BEX1 brain expressed, X-linked 1
CHSY1 chondroitin sulfate synthase 1
CLCN3 chloride channel, voltage-sensitive 3
CTSH cathepsin H
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
DCLK1 doublecortin-like kinase 1
FGF13 fibroblast growth factor 13
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXA1 forkhead box A1
GDE1 glycerophosphodiester phosphodiesterase 1
HOXA10 homeobox A10
IGHM immunoglobulin heavy constant mu
KAT6A K(lysine) acetyltransferase 6A
KIAA0101 KIAA0101
KLHL9 kelch-like family member 9
LBR lamin B receptor
LGALS1 lectin, galactoside-binding, soluble, 1
MAPK6 mitogen-activated protein kinase 6
NRIP1 nuclear receptor interacting protein 1
PANK3 pantothenate kinase 3
PSPH phosphoserine phosphatase
PTX3 pentraxin 3, long
RAB11FIP2 RAB11 family interacting protein 2 (class I)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM251 transmembrane protein 251
TYMS thymidylate synthetase
ZBTB18 zinc finger and BTB domain containing 18
ZNF106 zinc finger protein 106