| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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85 genes differentially expressed following the BRD-K74797618_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CD163 | CD163 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| HEPH | hephaestin |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST2H2BE | histone cluster 2, H2be |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| IFRD1 | interferon-related developmental regulator 1 |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLF4 | Kruppel-like factor 4 (gut) |
| MAGEA3 | melanoma antigen family A3 |
| MCL1 | myeloid cell leukemia 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ODC1 | ornithine decarboxylase 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RGCC | regulator of cell cycle |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRGN | serglycin |
| TRIB1 | tribbles pseudokinase 1 |
| TUFT1 | tuftelin 1 |
| UST | uronyl-2-sulfotransferase |
| Symbol | Name |
|---|---|
| AGTR1 | angiotensin II receptor, type 1 |
| ATF5 | activating transcription factor 5 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B3GNT1 | |
| CANT1 | calcium activated nucleotidase 1 |
| CD24 | CD24 molecule |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYB561 | cytochrome b561 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| KRT14 | keratin 14, type I |
| MGP | matrix Gla protein |
| MMP7 | matrix metallopeptidase 7 |
| MREG | melanoregulin |
| NFIB | nuclear factor I/B |
| NPY1R | neuropeptide Y receptor Y1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| OBSL1 | obscurin-like 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PAX5 | paired box 5 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| WFDC2 | WAP four-disulfide core domain 2 |
