BRD-K75532464_FTI-276 Trifluoroacetate_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K75532464_FTI-276 Trifluoroacetate_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY1 adenylate cyclase 1 (brain)
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD52 CD52 molecule
DEPTOR DEP domain containing MTOR-interacting protein
DLD dihydrolipoamide dehydrogenase
DNM1L dynamin 1-like
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPNMB glycoprotein (transmembrane) nmb
HDGFRP3 hepatoma-derived growth factor, related protein 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
NOV nephroblastoma overexpressed
PEA15 phosphoprotein enriched in astrocytes 15
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PTPRF protein tyrosine phosphatase, receptor type, F
RAD23B RAD23 homolog B (S. cerevisiae)
RSRP1 arginine/serine-rich protein 1
S100A13 S100 calcium binding protein A13
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STS steroid sulfatase (microsomal), isozyme S
TMSB15A thymosin beta 15a
TRIB1 tribbles pseudokinase 1
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ASCL1 achaete-scute family bHLH transcription factor 1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CALCA calcitonin-related polypeptide alpha
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CELF2 CUGBP, Elav-like family member 2
COTL1 coactosin-like F-actin binding protein 1
FAM46A family with sequence similarity 46, member A
FCGBP Fc fragment of IgG binding protein
FLG filaggrin
GPM6B glycoprotein M6B
HBB hemoglobin, beta
IL6ST interleukin 6 signal transducer
KIAA0226L KIAA0226-like
LAMP5 lysosomal-associated membrane protein family, member 5
LOR loricrin
LPL lipoprotein lipase
NAV3 neuron navigator 3
PLK2 polo-like kinase 2
RBP1 retinol binding protein 1, cellular
RHOBTB3 Rho-related BTB domain containing 3
SIDT2 SID1 transmembrane family, member 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSFA2 sperm specific antigen 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TP53 tumor protein p53
TUBB2A tubulin, beta 2A class IIa
ZIC1 Zic family member 1