BRD-K76236182_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K76236182_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AMDHD2 amidohydrolase domain containing 2
COLEC12 collectin sub-family member 12
CRABP2 cellular retinoic acid binding protein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
FASN fatty acid synthase
GSDMB gasdermin B
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IGFBP4 insulin-like growth factor binding protein 4
MAP7 microtubule-associated protein 7
MFAP2 microfibrillar-associated protein 2
MGP matrix Gla protein
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLPH melanophilin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX1 pre-B-cell leukemia homeobox 1
PDIA3 protein disulfide isomerase family A, member 3
RAP1GAP RAP1 GTPase activating protein
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELENBP1 selenium binding protein 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
THBS4 thrombospondin 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSKU tsukushi, small leucine rich proteoglycan
VIM vimentin

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL20 chemokine (C-C motif) ligand 20
CHMP4A charged multivesicular body protein 4A
COL5A2 collagen, type V, alpha 2
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
HSPA1A heat shock 70kDa protein 1A
IL18 interleukin 18
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MSH6 mutS homolog 6
PAEP progestagen-associated endometrial protein
PAK1IP1 PAK1 interacting protein 1
PCDH9 protocadherin 9
PLA2G15 phospholipase A2, group XV
SFN stratifin
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
TMEM251 transmembrane protein 251
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
Funding