BRD-K76401790_JNK-IN-5A_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BAX BCL2-associated X protein
CCNG1 cyclin G1
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DDB2 damage-specific DNA binding protein 2, 48kDa
DHRS2 dehydrogenase/reductase (SDR family) member 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR2 early growth response 2
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HIST1H2BK histone cluster 1, H2bk
IER5 immediate early response 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PLK2 polo-like kinase 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
RPS27L ribosomal protein S27-like
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNIP1 TNFAIP3 interacting protein 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
CDK1 cyclin-dependent kinase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
HES1 hes family bHLH transcription factor 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Funding