| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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150 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ANXA3 | annexin A3 |
| AURKA | aurora kinase A |
| AXL | AXL receptor tyrosine kinase |
| BAMBI | BMP and activin membrane-bound inhibitor |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CCND2 | cyclin D2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC20 | cell division cycle 20 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLIC3 | chloride intracellular channel 3 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| COL10A1 | collagen, type X, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTGF | connective tissue growth factor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DSG3 | desmoglein 3 |
| DST | dystonin |
| EDN3 | endothelin 3 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ELANE | elastase, neutrophil expressed |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| FSTL1 | follistatin-like 1 |
| GPM6B | glycoprotein M6B |
| HBEGF | heparin-binding EGF-like growth factor |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| INHBB | inhibin, beta B |
| IRS2 | insulin receptor substrate 2 |
| KIF20A | kinesin family member 20A |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| KRT5 | keratin 5, type II |
| KRT7 | keratin 7, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LHFP | lipoma HMGIC fusion partner |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LTF | lactotransferrin |
| MATN2 | matrilin 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NELL2 | NEL-like 2 (chicken) |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OBSL1 | obscurin-like 1 |
| PDZD8 | PDZ domain containing 8 |
| PODXL | podocalyxin-like |
| POSTN | periostin, osteoblast specific factor |
| PRDX2 | peroxiredoxin 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| S100A2 | S100 calcium binding protein A2 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFN | stratifin |
| SLPI | secretory leukocyte peptidase inhibitor |
| STAR | steroidogenic acute regulatory protein |
| STC2 | stanniocalcin 2 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SYBU | syntabulin (syntaxin-interacting) |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM29 | tripartite motif containing 29 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP6NL | USP6 N-terminal like |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BCHE | butyrylcholinesterase |
| CA12 | carbonic anhydrase XII |
| CD200 | CD200 molecule |
| CDK1 | cyclin-dependent kinase 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHEK2 | checkpoint kinase 2 |
| CLTA | clathrin, light chain A |
| COL1A1 | collagen, type I, alpha 1 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP6 | dual specificity phosphatase 6 |
| EMX2 | empty spiracles homeobox 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GPX2 | glutathione peroxidase 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HBB | hemoglobin, beta |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA1A | heat shock 70kDa protein 1A |
| MELK | maternal embryonic leucine zipper kinase |
| MFAP4 | microfibrillar-associated protein 4 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYRF | myelin regulatory factor |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NGRN | neugrin, neurite outgrowth associated |
| NID2 | nidogen 2 (osteonidogen) |
| PLIN2 | perilipin 2 |
| PRKCD | protein kinase C, delta |
| PSPH | phosphoserine phosphatase |
| QPCT | glutaminyl-peptide cyclotransferase |
| REEP1 | receptor accessory protein 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SV2C | synaptic vesicle glycoprotein 2C |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TESC | tescalcin |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TMSB15A | thymosin beta 15a |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPAN8 | tetraspanin 8 |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| VCAM1 | vascular cell adhesion molecule 1 |
