BRD-K76694128_DCC-2036_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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61 genes differentially expressed following the BRD-K76694128_DCC-2036_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADARB1 adenosine deaminase, RNA-specific, B1
AMIGO2 adhesion molecule with Ig-like domain 2
ARL4C ADP-ribosylation factor-like 4C
BPTF bromodomain PHD finger transcription factor
CA12 carbonic anhydrase XII
CCND1 cyclin D1
CCND2 cyclin D2
CDCP1 CUB domain containing protein 1
COL4A6 collagen, type IV, alpha 6
CRYAB crystallin, alpha B
CTSZ cathepsin Z
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP7 fatty acid binding protein 7, brain
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GLRX glutaredoxin (thioltransferase)
HIST1H4C histone cluster 1, H4c
KLK5 kallikrein-related peptidase 5
KRT5 keratin 5, type II
LCN2 lipocalin 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MGLL monoglyceride lipase
MT1M metallothionein 1M
NAV3 neuron navigator 3
PTHLH parathyroid hormone-like hormone
RTN2 reticulon 2
S100P S100 calcium binding protein P
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLIT2 slit homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
TCF4 transcription factor 4
TCTN1 tectonic family member 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZBED2 zinc finger, BED-type containing 2
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
CALCA calcitonin-related polypeptide alpha
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP2 cysteine and glycine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAXX death-domain associated protein
DEPTOR DEP domain containing MTOR-interacting protein
EBP emopamil binding protein (sterol isomerase)
GPX4 glutathione peroxidase 4
HLA-B major histocompatibility complex, class I, B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
MAL mal, T-cell differentiation protein
NRGN neurogranin (protein kinase C substrate, RC3)
OLFML2B olfactomedin-like 2B
PCP4 Purkinje cell protein 4
PRR7 proline rich 7 (synaptic)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1