BRD-K76694128_DCC-2036_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K76694128_DCC-2036_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANOS1 anosmin 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
CTSK cathepsin K
CXCL5 chemokine (C-X-C motif) ligand 5
DMTF1 cyclin D binding myb-like transcription factor 1
DRAM1 DNA-damage regulated autophagy modulator 1
ESR1 estrogen receptor 1
FGFR3 fibroblast growth factor receptor 3
GADD45B growth arrest and DNA-damage-inducible, beta
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
LIMCH1 LIM and calponin homology domains 1
MYOF myoferlin
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PIR pirin (iron-binding nuclear protein)
PMP22 peripheral myelin protein 22
PPAP2C phosphatidic acid phosphatase type 2C
SFRP4 secreted frizzled-related protein 4
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TM4SF1 transmembrane 4 L six family member 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BZW2 basic leucine zipper and W2 domains 2
CD14 CD14 molecule
CHERP calcium homeostasis endoplasmic reticulum protein
CORO1A coronin, actin binding protein, 1A
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
FGFBP1 fibroblast growth factor binding protein 1
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
GAGE3 G antigen 3
GPX3 glutathione peroxidase 3
GRB10 growth factor receptor-bound protein 10
HMOX1 heme oxygenase 1
IER3 immediate early response 3
KRT23 keratin 23, type I
KRT6A keratin 6A, type II
LCN2 lipocalin 2
LTF lactotransferrin
LYZ lysozyme
MAGEA3 melanoma antigen family A3
MELK maternal embryonic leucine zipper kinase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP9 matrix metallopeptidase 9
NDRG1 N-myc downstream regulated 1
NRN1 neuritin 1
PAPD7 PAP associated domain containing 7
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
REG1A regenerating islet-derived 1 alpha
RUNX3 runt-related transcription factor 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMTN smoothelin
TBC1D4 TBC1 domain family, member 4
TNC tenascin C
TNS1 tensin 1
TUBB2A tubulin, beta 2A class IIa
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
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