BRD-K76908866_CP-724714_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K76908866_CP-724714_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACACB acetyl-CoA carboxylase beta
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA5 annexin A5
CFD complement factor D (adipsin)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FBXL12 F-box and leucine-rich repeat protein 12
FGFR2 fibroblast growth factor receptor 2
FOXF2 forkhead box F2
GAS6 growth arrest-specific 6
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IL6 interleukin 6
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
LEPR leptin receptor
LRRC32 leucine rich repeat containing 32
MATN2 matrilin 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOV nephroblastoma overexpressed
PLAU plasminogen activator, urokinase
PRDX2 peroxiredoxin 2
PSCA prostate stem cell antigen
S100A2 S100 calcium binding protein A2
SCGB2A2 secretoglobin, family 2A, member 2
SDC4 syndecan 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPINK1 serine peptidase inhibitor, Kazal type 1
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TMEM255A transmembrane protein 255A
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC1 WAP four-disulfide core domain 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
BEX1 brain expressed, X-linked 1
CENPA centromere protein A
CHN1 chimerin 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL galanin/GMAP prepropeptide
GNAS GNAS complex locus
GRB14 growth factor receptor-bound protein 14
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFRD2 interferon-related developmental regulator 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF20A kinesin family member 20A
LMO3 LIM domain only 3 (rhombotin-like 2)
MDK midkine (neurite growth-promoting factor 2)
NPTX2 neuronal pentraxin II
PCDH9 protocadherin 9
PLK1 polo-like kinase 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RRM2 ribonucleotide reductase M2
RTN1 reticulon 1
TIMP3 TIMP metallopeptidase inhibitor 3
Funding