Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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107 genes differentially expressed following the BRD-K76908866_CP-724714_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AGR2 | anterior gradient 2 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
AUTS2 | autism susceptibility candidate 2 |
BTG1 | B-cell translocation gene 1, anti-proliferative |
C6ORF48 | chromosome 6 open reading frame 48 |
CAPN1 | calpain 1, (mu/I) large subunit |
CD302 | CD302 molecule |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CLMN | calmin (calponin-like, transmembrane) |
CPD | carboxypeptidase D |
CST3 | cystatin C |
CST4 | cystatin S |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
ESR1 | estrogen receptor 1 |
EXPH5 | exophilin 5 |
EYA2 | EYA transcriptional coactivator and phosphatase 2 |
GLUL | glutamate-ammonia ligase |
HDAC6 | histone deacetylase 6 |
HECA | headcase homolog (Drosophila) |
HNMT | histamine N-methyltransferase |
IDO1 | indoleamine 2,3-dioxygenase 1 |
KAT6B | K(lysine) acetyltransferase 6B |
KIZ | kizuna centrosomal protein |
KRT19 | keratin 19, type I |
LIMK2 | LIM domain kinase 2 |
LOC100272216 | uncharacterized LOC100272216 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
METTL7A | methyltransferase like 7A |
MLPH | melanophilin |
MUC16 | mucin 16, cell surface associated |
MUC4 | mucin 4, cell surface associated |
MVP | major vault protein |
OBSL1 | obscurin-like 1 |
PALLD | palladin, cytoskeletal associated protein |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
PDGFRL | platelet-derived growth factor receptor-like |
PRUNE | prune exopolyphosphatase |
RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
S100P | S100 calcium binding protein P |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SELENBP1 | selenium binding protein 1 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SIX1 | SIX homeobox 1 |
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
SNAI2 | snail family zinc finger 2 |
TM9SF3 | transmembrane 9 superfamily member 3 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRIM2 | tripartite motif containing 2 |
TXNIP | thioredoxin interacting protein |
WFDC2 | WAP four-disulfide core domain 2 |
XBP1 | X-box binding protein 1 |
Symbol | Name |
---|---|
AQP1 | aquaporin 1 (Colton blood group) |
ATAD2 | ATPase family, AAA domain containing 2 |
AURKA | aurora kinase A |
BIRC5 | baculoviral IAP repeat containing 5 |
CA2 | carbonic anhydrase II |
CCNA2 | cyclin A2 |
CCND1 | cyclin D1 |
CCND2 | cyclin D2 |
CD52 | CD52 molecule |
CDC20 | cell division cycle 20 |
CDC25A | cell division cycle 25A |
CDK1 | cyclin-dependent kinase 1 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
EDNRB | endothelin receptor type B |
FXYD5 | FXYD domain containing ion transport regulator 5 |
GAL | galanin/GMAP prepropeptide |
GLIPR1 | GLI pathogenesis-related 1 |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HMG20B | high mobility group 20B |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IFI6 | interferon, alpha-inducible protein 6 |
JMJD6 | jumonji domain containing 6 |
KIF20A | kinesin family member 20A |
KRT14 | keratin 14, type I |
LAGE3 | L antigen family, member 3 |
LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
NCAPG | non-SMC condensin I complex, subunit G |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
NPTX2 | neuronal pentraxin II |
NPY | neuropeptide Y |
PBK | PDZ binding kinase |
PLK1 | polo-like kinase 1 |
POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
POSTN | periostin, osteoblast specific factor |
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
RBP1 | retinol binding protein 1, cellular |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SRM | spermidine synthase |
TACC3 | transforming, acidic coiled-coil containing protein 3 |
TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
TNC | tenascin C |
TSPAN13 | tetraspanin 13 |
TSPYL5 | TSPY-like 5 |
TUBA4A | tubulin, alpha 4a |
UBE2C | ubiquitin-conjugating enzyme E2C |
UBE2S | ubiquitin-conjugating enzyme E2S |
UPP1 | uridine phosphorylase 1 |
VIM | vimentin |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |