Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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118 genes differentially expressed following the BRD-K76908866_CP-724714_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
ADD3 | adducin 3 (gamma) |
ANO1 | anoctamin 1, calcium activated chloride channel |
BHLHE40 | basic helix-loop-helix family, member e40 |
CAPN1 | calpain 1, (mu/I) large subunit |
CD300A | CD300a molecule |
CLDN3 | claudin 3 |
CLMN | calmin (calponin-like, transmembrane) |
CPT1A | carnitine palmitoyltransferase 1A (liver) |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DUSP14 | dual specificity phosphatase 14 |
EFNA1 | ephrin-A1 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
EXPH5 | exophilin 5 |
FOXN3 | forkhead box N3 |
GAB2 | GRB2-associated binding protein 2 |
GAS6 | growth arrest-specific 6 |
GLUL | glutamate-ammonia ligase |
GRB7 | growth factor receptor-bound protein 7 |
GSE1 | Gse1 coiled-coil protein |
GSTM3 | glutathione S-transferase mu 3 (brain) |
GSTT1 | glutathione S-transferase theta 1 |
HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
HNMT | histamine N-methyltransferase |
KIAA1033 | KIAA1033 |
KRT19 | keratin 19, type I |
LXN | latexin |
MLPH | melanophilin |
MUC1 | mucin 1, cell surface associated |
MVP | major vault protein |
NEBL | nebulette |
NPDC1 | neural proliferation, differentiation and control, 1 |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCARB2 | scavenger receptor class B, member 2 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SCPEP1 | serine carboxypeptidase 1 |
SECISBP2L | SECIS binding protein 2-like |
SELENBP1 | selenium binding protein 1 |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SPDEF | SAM pointed domain containing ETS transcription factor |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TSC22D1 | TSC22 domain family, member 1 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
VWA5A | von Willebrand factor A domain containing 5A |
WRB | tryptophan rich basic protein |
XBP1 | X-box binding protein 1 |
ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABAT | 4-aminobutyrate aminotransferase |
AEBP1 | AE binding protein 1 |
ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
ATAD2 | ATPase family, AAA domain containing 2 |
BIRC5 | baculoviral IAP repeat containing 5 |
CCNA2 | cyclin A2 |
CCND3 | cyclin D3 |
CCNE2 | cyclin E2 |
CDC20 | cell division cycle 20 |
CDC25A | cell division cycle 25A |
CDC42 | cell division cycle 42 |
CDC6 | cell division cycle 6 |
CDK1 | cyclin-dependent kinase 1 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CENPA | centromere protein A |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CSRP1 | cysteine and glycine-rich protein 1 |
DCK | deoxycytidine kinase |
DLK1 | delta-like 1 homolog (Drosophila) |
DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
EBP | emopamil binding protein (sterol isomerase) |
EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
FGFR2 | fibroblast growth factor receptor 2 |
FN1 | fibronectin 1 |
FOXM1 | forkhead box M1 |
GAL | galanin/GMAP prepropeptide |
GCH1 | GTP cyclohydrolase 1 |
GINS1 | GINS complex subunit 1 (Psf1 homolog) |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GTSE1 | G-2 and S-phase expressed 1 |
HBB | hemoglobin, beta |
HIST1H4C | histone cluster 1, H4c |
IGL | immunoglobulin lambda locus |
IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
IL13RA2 | interleukin 13 receptor, alpha 2 |
KIF18B | kinesin family member 18B |
KPNA3 | karyopherin alpha 3 (importin alpha 4) |
LAGE3 | L antigen family, member 3 |
LAPTM5 | lysosomal protein transmembrane 5 |
LMNB1 | lamin B1 |
LSM12 | LSM12 homolog (S. cerevisiae) |
LTF | lactotransferrin |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
MKI67 | marker of proliferation Ki-67 |
NPY1R | neuropeptide Y receptor Y1 |
NUSAP1 | nucleolar and spindle associated protein 1 |
PBK | PDZ binding kinase |
PLK1 | polo-like kinase 1 |
POSTN | periostin, osteoblast specific factor |
PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RRM2 | ribonucleotide reductase M2 |
SPP1 | secreted phosphoprotein 1 |
STMN1 | stathmin 1 |
SULF1 | sulfatase 1 |
TLR4 | toll-like receptor 4 |
TMEM97 | transmembrane protein 97 |
TNC | tenascin C |
TPM1 | tropomyosin 1 (alpha) |
TUBG1 | tubulin, gamma 1 |
UBE2C | ubiquitin-conjugating enzyme E2C |
VCAM1 | vascular cell adhesion molecule 1 |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
ZWINT | ZW10 interacting kinetochore protein |