BRD-K76938712_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K76938712_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ATM ATM serine/threonine kinase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRABP2 cellular retinoic acid binding protein 2
DAD1 defender against cell death 1
DDIT4 DNA-damage-inducible transcript 4
ENO2 enolase 2 (gamma, neuronal)
EYA1 EYA transcriptional coactivator and phosphatase 1
FADS1 fatty acid desaturase 1
FCGBP Fc fragment of IgG binding protein
FKBP14 FK506 binding protein 14, 22 kDa
GAP43 growth associated protein 43
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
IER3 immediate early response 3
NUCB2 nucleobindin 2
P4HB prolyl 4-hydroxylase, beta polypeptide
PCP4 Purkinje cell protein 4
PDIA3 protein disulfide isomerase family A, member 3
PDIA4 protein disulfide isomerase family A, member 4
PECAM1 platelet/endothelial cell adhesion molecule 1
SCG2 secretogranin II
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A4 solute carrier family 16, member 4
SOX9 SRY (sex determining region Y)-box 9
SRGN serglycin
TMEM45A transmembrane protein 45A
TXNIP thioredoxin interacting protein
VAT1 vesicle amine transport 1
VWF von Willebrand factor

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
BLCAP bladder cancer associated protein
BMI1 BMI1 proto-oncogene, polycomb ring finger
BTBD3 BTB (POZ) domain containing 3
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNE2 cyclin E2
DCN decorin
EGR3 early growth response 3
FGF13 fibroblast growth factor 13
LAPTM4B lysosomal protein transmembrane 4 beta
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LUM lumican
NCOA2 nuclear receptor coactivator 2
PCNA proliferating cell nuclear antigen
PLAGL1 pleiomorphic adenoma gene-like 1
SGMS1 sphingomyelin synthase 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
Funding