Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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149 genes differentially expressed following the BRD-K77286328_R3904_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
ACACB | acetyl-CoA carboxylase beta |
ADD3 | adducin 3 (gamma) |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
ANOS1 | anosmin 1 |
AOC3 | amine oxidase, copper containing 3 |
APOD | apolipoprotein D |
ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 |
ARL4C | ADP-ribosylation factor-like 4C |
ASPN | asporin |
ATP9A | ATPase, class II, type 9A |
C1R | complement component 1, r subcomponent |
C3 | complement component 3 |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CD93 | CD93 molecule |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CES1 | carboxylesterase 1 |
CFD | complement factor D (adipsin) |
CHRDL1 | chordin-like 1 |
CLU | clusterin |
COL14A1 | collagen, type XIV, alpha 1 |
COL15A1 | collagen, type XV, alpha 1 |
CSF1R | colony stimulating factor 1 receptor |
CTSF | cathepsin F |
CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
DCLK1 | doublecortin-like kinase 1 |
DCN | decorin |
DMD | dystrophin |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM129A | family with sequence similarity 129, member A |
FAM198B | family with sequence similarity 198, member B |
FBLN1 | fibulin 1 |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GAS1 | growth arrest-specific 1 |
GHR | growth hormone receptor |
GPM6B | glycoprotein M6B |
H1FX | H1 histone family, member X |
HES1 | hes family bHLH transcription factor 1 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
IGHM | immunoglobulin heavy constant mu |
IL1R1 | interleukin 1 receptor, type I |
IQGAP1 | IQ motif containing GTPase activating protein 1 |
ITM2A | integral membrane protein 2A |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
METTL7A | methyltransferase like 7A |
MTUS1 | microtubule associated tumor suppressor 1 |
MXRA5 | matrix-remodelling associated 5 |
NBPF10 | neuroblastoma breakpoint family, member 10 |
NCAM1 | neural cell adhesion molecule 1 |
NDRG2 | NDRG family member 2 |
PDGFD | platelet derived growth factor D |
PDGFRL | platelet-derived growth factor receptor-like |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
RTN2 | reticulon 2 |
SFRP4 | secreted frizzled-related protein 4 |
SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
ST18 | suppression of tumorigenicity 18, zinc finger |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
SVIL | supervillin |
SYBU | syntabulin (syntaxin-interacting) |
TCEA2 | transcription elongation factor A (SII), 2 |
TPP1 | tripeptidyl peptidase I |
TRD | T cell receptor delta locus |
TRDV3 | T cell receptor delta variable 3 |
TSPAN7 | tetraspanin 7 |
Symbol | Name |
---|---|
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ACAT2 | acetyl-CoA acetyltransferase 2 |
ACLY | ATP citrate lyase |
ALCAM | activated leukocyte cell adhesion molecule |
ALDOC | aldolase C, fructose-bisphosphate |
AMD1 | adenosylmethionine decarboxylase 1 |
ATP11B | ATPase, class VI, type 11B |
BEX1 | brain expressed, X-linked 1 |
BIRC5 | baculoviral IAP repeat containing 5 |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
BOP1 | block of proliferation 1 |
CA12 | carbonic anhydrase XII |
CCNA2 | cyclin A2 |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CD59 | CD59 molecule, complement regulatory protein |
CDC20 | cell division cycle 20 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
DHCR7 | 7-dehydrocholesterol reductase |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EBNA1BP2 | EBNA1 binding protein 2 |
ELOVL1 | ELOVL fatty acid elongase 1 |
EREG | epiregulin |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FAM216A | family with sequence similarity 216, member A |
FKBP11 | FK506 binding protein 11, 19 kDa |
FOSL1 | FOS-like antigen 1 |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
LDLR | low density lipoprotein receptor |
LOX | lysyl oxidase |
LTF | lactotransferrin |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
MAGED1 | melanoma antigen family D1 |
MELK | maternal embryonic leucine zipper kinase |
MSMO1 | methylsterol monooxygenase 1 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NFIL3 | nuclear factor, interleukin 3 regulated |
NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
NPY | neuropeptide Y |
ODC1 | ornithine decarboxylase 1 |
P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PFKP | phosphofructokinase, platelet |
PGK1 | phosphoglycerate kinase 1 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PNP | purine nucleoside phosphorylase |
PTTG1 | pituitary tumor-transforming 1 |
RCAN1 | regulator of calcineurin 1 |
RGS4 | regulator of G-protein signaling 4 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SPAG4 | sperm associated antigen 4 |
SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
TAGLN | transgelin |
TFRC | transferrin receptor |
THBS1 | thrombospondin 1 |
TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TRIP13 | thyroid hormone receptor interactor 13 |
TUBB6 | tubulin, beta 6 class V |
TYMS | thymidylate synthetase |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
UBE2C | ubiquitin-conjugating enzyme E2C |
VDAC1 | voltage-dependent anion channel 1 |
WSB2 | WD repeat and SOCS box containing 2 |