BRD-K77286328_R3904_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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89 genes differentially expressed following the BRD-K77286328_R3904_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTBP2 C-terminal binding protein 2
DPYSL3 dihydropyrimidinase-like 3
ESR1 estrogen receptor 1
GLUL glutamate-ammonia ligase
H3F3B H3 histone, family 3B (H3.3B)
HBB hemoglobin, beta
HSPA13 heat shock protein 70kDa family, member 13
IFITM1 interferon induced transmembrane protein 1
IGHD immunoglobulin heavy constant delta
MAOA monoamine oxidase A
MFAP2 microfibrillar-associated protein 2
OSR2 odd-skipped related transciption factor 2
PBX3 pre-B-cell leukemia homeobox 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PXDN peroxidasin
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TSC22D3 TSC22 domain family, member 3
TUBB2B tubulin, beta 2B class IIb

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANO1 anoctamin 1, calcium activated chloride channel
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BIRC3 baculoviral IAP repeat containing 3
CAPN3 calpain 3, (p94)
CCNA2 cyclin A2
CCND1 cyclin D1
CD52 CD52 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CES1 carboxylesterase 1
CFI complement factor I
COCH cochlin
CRYZ crystallin, zeta (quinone reductase)
CST7 cystatin F (leukocystatin)
CTSC cathepsin C
CXCL13 chemokine (C-X-C motif) ligand 13
DLK1 delta-like 1 homolog (Drosophila)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBN1 fibrillin 1
FGFR4 fibroblast growth factor receptor 4
GOLGA8A golgin A8 family, member A
GPI glucose-6-phosphate isomerase
GPX2 glutathione peroxidase 2
GSAP gamma-secretase activating protein
HNMT histamine N-methyltransferase
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSPB1 heat shock 27kDa protein 1
KLK6 kallikrein-related peptidase 6
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MDK midkine (neurite growth-promoting factor 2)
MNDA myeloid cell nuclear differentiation antigen
MSMB microseminoprotein, beta-
MYCBP MYC binding protein
MYRF myelin regulatory factor
NPY1R neuropeptide Y receptor Y1
NTS neurotensin
PHLDA2 pleckstrin homology-like domain, family A, member 2
PKP1 plakophilin 1
PRAME preferentially expressed antigen in melanoma
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRSS23 protease, serine, 23
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RPS11 ribosomal protein S11
S100A7 S100 calcium binding protein A7
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A4 solute carrier family 16, member 4
SLPI secretory leukocyte peptidase inhibitor
SPRR3 small proline-rich protein 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TMEM47 transmembrane protein 47
TOX3 TOX high mobility group box family member 3
TRIM29 tripartite motif containing 29
TRIM38 tripartite motif containing 38