| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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148 genes differentially expressed following the BRD-K77547509_3-cyclohexyl-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-2,4(1H,3H)-dione_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| CD99 | CD99 molecule |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CLU | clusterin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTA | cystatin A (stefin A) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DSG3 | desmoglein 3 |
| DUSP14 | dual specificity phosphatase 14 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EMP1 | epithelial membrane protein 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| EZR | ezrin |
| FASTKD5 | FAST kinase domains 5 |
| FBXO11 | F-box protein 11 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FN1 | fibronectin 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GSTP1 | glutathione S-transferase pi 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| INSIG1 | insulin induced gene 1 |
| IRX5 | iroquois homeobox 5 |
| ISCA1 | iron-sulfur cluster assembly 1 |
| JUP | junction plakoglobin |
| KLHL7 | kelch-like family member 7 |
| KRT4 | keratin 4, type II |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LCN2 | lipocalin 2 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MTSS1 | metastasis suppressor 1 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NDRG1 | N-myc downstream regulated 1 |
| NPY | neuropeptide Y |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PRDX1 | peroxiredoxin 1 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRSS8 | protease, serine, 8 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| S100A10 | S100 calcium binding protein A10 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SELENBP1 | selenium binding protein 1 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOX4 | SRY (sex determining region Y)-box 4 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TSC22D1 | TSC22 domain family, member 1 |
| TSPAN7 | tetraspanin 7 |
| TUBA1A | tubulin, alpha 1a |
| VAT1 | vesicle amine transport 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AREG | amphiregulin |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATM | ATM serine/threonine kinase |
| ATR | ATR serine/threonine kinase |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CAPRIN2 | caprin family member 2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK12 | cyclin-dependent kinase 12 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| ETV5 | ets variant 5 |
| EXOC1 | exocyst complex component 1 |
| FAM13A | family with sequence similarity 13, member A |
| FBN1 | fibrillin 1 |
| FHL2 | four and a half LIM domains 2 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GOLGA8A | golgin A8 family, member A |
| GPX2 | glutathione peroxidase 2 |
| GSAP | gamma-secretase activating protein |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| INTS3 | integrator complex subunit 3 |
| JADE2 | jade family PHD finger 2 |
| LOC100505650 | uncharacterized LOC100505650 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MECOM | MDS1 and EVI1 complex locus |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFAP5 | microfibrillar associated protein 5 |
| MTCL1 | microtubule crosslinking factor 1 |
| MTDH | metadherin |
| MX1 | MX dynamin-like GTPase 1 |
| NFIB | nuclear factor I/B |
| NID2 | nidogen 2 (osteonidogen) |
| NMT1 | N-myristoyltransferase 1 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OXR1 | oxidation resistance 1 |
| OXTR | oxytocin receptor |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PLXDC1 | plexin domain containing 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RBBP8 | retinoblastoma binding protein 8 |
| RECQL | RecQ helicase-like |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEH1L | SEH1-like (S. cerevisiae) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC38A2 | solute carrier family 38, member 2 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPG11 | spastic paraplegia 11 (autosomal recessive) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STAMBP | STAM binding protein |
| STAR | steroidogenic acute regulatory protein |
| TCERG1 | transcription elongation regulator 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TMEM2 | transmembrane protein 2 |
| TMEM5 | transmembrane protein 5 |
| TRIP6 | thyroid hormone receptor interactor 6 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSPAN8 | tetraspanin 8 |
| UBE3C | ubiquitin protein ligase E3C |
| USO1 | USO1 vesicle transport factor |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF131 | zinc finger protein 131 |
| ZNF160 | zinc finger protein 160 |
