| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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122 genes differentially expressed following the BRD-K77625799_vandetanib_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| AGR2 | anterior gradient 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ASRGL1 | asparaginase like 1 |
| BAD | BCL2-associated agonist of cell death |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BLVRB | biliverdin reductase B |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCNG2 | cyclin G2 |
| CLDN10 | claudin 10 |
| CLU | clusterin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CST3 | cystatin C |
| CTSD | cathepsin D |
| CYBA | cytochrome b-245, alpha polypeptide |
| DHCR24 | 24-dehydrocholesterol reductase |
| DPP4 | dipeptidyl-peptidase 4 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBLN1 | fibulin 1 |
| FHL1 | four and a half LIM domains 1 |
| FLNA | filamin A, alpha |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GPX4 | glutathione peroxidase 4 |
| H1F0 | H1 histone family, member 0 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST3H2A | histone cluster 3, H2a |
| HMG20B | high mobility group 20B |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPB8 | heat shock 22kDa protein 8 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| MAL | mal, T-cell differentiation protein |
| MEIS1 | Meis homeobox 1 |
| MUC1 | mucin 1, cell surface associated |
| MYH10 | myosin, heavy chain 10, non-muscle |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDZK1 | PDZ domain containing 1 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PPL | periplakin |
| PRDX2 | peroxiredoxin 2 |
| PRKCB | protein kinase C, beta |
| PYCARD | PYD and CARD domain containing |
| QPRT | quinolinate phosphoribosyltransferase |
| REC8 | REC8 meiotic recombination protein |
| S100P | S100 calcium binding protein P |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLC44A4 | solute carrier family 44, member 4 |
| TKT | transketolase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPP1 | tripeptidyl peptidase I |
| TXNIP | thioredoxin interacting protein |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VAT1 | vesicle amine transport 1 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| AGO2 | argonaute RISC catalytic component 2 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNE2 | cyclin E2 |
| CDC42 | cell division cycle 42 |
| CDC45 | cell division cycle 45 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPHA3 | EPH receptor A3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FAM69A | family with sequence similarity 69, member A |
| FOSL1 | FOS-like antigen 1 |
| GPM6B | glycoprotein M6B |
| HBEGF | heparin-binding EGF-like growth factor |
| HES1 | hes family bHLH transcription factor 1 |
| IER3 | immediate early response 3 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| INHBA | inhibin, beta A |
| ITGA6 | integrin, alpha 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| MT1X | metallothionein 1X |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAT | plasminogen activator, tissue |
| PNP | purine nucleoside phosphorylase |
| RGS4 | regulator of G-protein signaling 4 |
| SCRG1 | stimulator of chondrogenesis 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| WDR43 | WD repeat domain 43 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
