Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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114 genes differentially expressed following the BRD-K77690805_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
ARG2 | arginase 2 |
ARL4C | ADP-ribosylation factor-like 4C |
ASPN | asporin |
ASS1 | argininosuccinate synthase 1 |
ATP11B | ATPase, class VI, type 11B |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CD93 | CD93 molecule |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
COL8A2 | collagen, type VIII, alpha 2 |
CPE | carboxypeptidase E |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DPT | dermatopontin |
DPYSL3 | dihydropyrimidinase-like 3 |
EML1 | echinoderm microtubule associated protein like 1 |
EPAS1 | endothelial PAS domain protein 1 |
ETV5 | ets variant 5 |
FILIP1L | filamin A interacting protein 1-like |
G0S2 | G0/G1 switch 2 |
GPNMB | glycoprotein (transmembrane) nmb |
GRB7 | growth factor receptor-bound protein 7 |
GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HADH | hydroxyacyl-CoA dehydrogenase |
HDAC9 | histone deacetylase 9 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
IDO1 | indoleamine 2,3-dioxygenase 1 |
IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
IGL | immunoglobulin lambda locus |
KCNK3 | potassium channel, two pore domain subfamily K, member 3 |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
MFAP5 | microfibrillar associated protein 5 |
MME | membrane metallo-endopeptidase |
MSLN | mesothelin |
PCLO | piccolo presynaptic cytomatrix protein |
PDZD2 | PDZ domain containing 2 |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PPOX | protoporphyrinogen oxidase |
PRKCI | protein kinase C, iota |
PRUNE2 | prune homolog 2 (Drosophila) |
PTN | pleiotrophin |
RGCC | regulator of cell cycle |
RGS5 | regulator of G-protein signaling 5 |
SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
SNX7 | sorting nexin 7 |
SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
ST18 | suppression of tumorigenicity 18, zinc finger |
STON1 | stonin 1 |
TCF4 | transcription factor 4 |
TES | testin LIM domain protein |
TMEM165 | transmembrane protein 165 |
TMSB15A | thymosin beta 15a |
TSPAN12 | tetraspanin 12 |
TUBA1A | tubulin, alpha 1a |
WARS | tryptophanyl-tRNA synthetase |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
AHNAK | AHNAK nucleoprotein |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
AQP3 | aquaporin 3 (Gill blood group) |
ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
BMI1 | BMI1 proto-oncogene, polycomb ring finger |
C2CD2 | C2 calcium-dependent domain containing 2 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
COMMD3 | COMM domain containing 3 |
CTSH | cathepsin H |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
F12 | coagulation factor XII (Hageman factor) |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FABP1 | fatty acid binding protein 1, liver |
FGF13 | fibroblast growth factor 13 |
HOXC10 | homeobox C10 |
HOXC6 | homeobox C6 |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IL6ST | interleukin 6 signal transducer |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
LTF | lactotransferrin |
LY6D | lymphocyte antigen 6 complex, locus D |
MAMLD1 | mastermind-like domain containing 1 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
MGP | matrix Gla protein |
MMP12 | matrix metallopeptidase 12 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PLS3 | plastin 3 |
PRAME | preferentially expressed antigen in melanoma |
PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
RAB14 | RAB14, member RAS oncogene family |
RPL38 | ribosomal protein L38 |
RPS11 | ribosomal protein S11 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SLPI | secretory leukocyte peptidase inhibitor |
SPATS2L | spermatogenesis associated, serine-rich 2-like |
STK17A | serine/threonine kinase 17a |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
THOC2 | THO complex 2 |
TLR4 | toll-like receptor 4 |
TMED2 | transmembrane emp24 domain trafficking protein 2 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TSPAN8 | tetraspanin 8 |
UBE2A | ubiquitin-conjugating enzyme E2A |
ZNF586 | zinc finger protein 586 |