BRD-K77908580_entinostat_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K77908580_entinostat_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADIRF adipogenesis regulatory factor
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
APOB apolipoprotein B
BTG3 BTG family, member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC42 cell division cycle 42
CFLAR CASP8 and FADD-like apoptosis regulator
CSRP1 cysteine and glycine-rich protein 1
DOCK4 dedicator of cytokinesis 4
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EPAS1 endothelial PAS domain protein 1
EPHA3 EPH receptor A3
FOLR1 folate receptor 1 (adult)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXA5 homeobox A5
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3 lectin, galactoside-binding, soluble, 3
LIMCH1 LIM and calponin homology domains 1
MT1E metallothionein 1E
NLRP2 NLR family, pyrin domain containing 2
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RBP1 retinol binding protein 1, cellular
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGM2 transglutaminase 2
TMSB15A thymosin beta 15a

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADAM28 ADAM metallopeptidase domain 28
ADI1 acireductone dioxygenase 1
BEX1 brain expressed, X-linked 1
BLCAP bladder cancer associated protein
CALB1 calbindin 1, 28kDa
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
FHL1 four and a half LIM domains 1
FXYD3 FXYD domain containing ion transport regulator 3
GJA1 gap junction protein, alpha 1, 43kDa
GLUD1 glutamate dehydrogenase 1
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
KIAA0125 KIAA0125
OBSL1 obscurin-like 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
ZFP36L2 ZFP36 ring finger protein-like 2
ZIC1 Zic family member 1
Funding