BRD-K77908580_entinostat_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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58 genes differentially expressed following the BRD-K77908580_entinostat_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD2 abhydrolase domain containing 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
BMP2 bone morphogenetic protein 2
C3ORF14 chromosome 3 open reading frame 14
C6ORF62 chromosome 6 open reading frame 62
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CXCL8 chemokine (C-X-C motif) ligand 8
EVI2B ecotropic viral integration site 2B
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
G0S2 G0/G1 switch 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
IGKC immunoglobulin kappa constant
INHBA inhibin, beta A
ISG20 interferon stimulated exonuclease gene 20kDa
IVNS1ABP influenza virus NS1A binding protein
KLF11 Kruppel-like factor 11
KLF6 Kruppel-like factor 6
MNAT1 MNAT CDK-activating kinase assembly factor 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NRCAM neuronal cell adhesion molecule
OAT ornithine aminotransferase
PAN2 PAN2 poly(A) specific ribonuclease subunit
POSTN periostin, osteoblast specific factor
RBP1 retinol binding protein 1, cellular
SERTAD2 SERTA domain containing 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SNAP25 synaptosomal-associated protein, 25kDa
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
CEP57 centrosomal protein 57kDa
CFB complement factor B
DPP4 dipeptidyl-peptidase 4
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
GSTA1 glutathione S-transferase alpha 1
HOPX HOP homeobox
LY6E lymphocyte antigen 6 complex, locus E
MKNK1 MAP kinase interacting serine/threonine kinase 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAPD7 PAP associated domain containing 7
PCNA proliferating cell nuclear antigen
RAI14 retinoic acid induced 14
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFRP1 secreted frizzled-related protein 1
SUB1 SUB1 homolog (S. cerevisiae)
TFF1 trefoil factor 1
TUBB tubulin, beta class I
WNT5A wingless-type MMTV integration site family, member 5A