BRD-K77987382_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K77987382_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGAP29 Rho GTPase activating protein 29
CAV1 caveolin 1, caveolae protein, 22kDa
CTGF connective tissue growth factor
FGFR2 fibroblast growth factor receptor 2
FHL2 four and a half LIM domains 2
GADD45B growth arrest and DNA-damage-inducible, beta
GAS6 growth arrest-specific 6
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
JUN jun proto-oncogene
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1E metallothionein 1E
MTMR11 myotubularin related protein 11
MYO1D myosin ID
NEB nebulin
NT5E 5'-nucleotidase, ecto (CD73)
OPTN optineurin
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSRP2 cysteine and glycine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
EDNRB endothelin receptor type B
ETV1 ets variant 1
GPM6B glycoprotein M6B
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
MARCKSL1 MARCKS-like 1
MLEC malectin
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NRCAM neuronal cell adhesion molecule
PIR pirin (iron-binding nuclear protein)