| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
163 genes differentially expressed following the BRD-K77987382_Mebendazole_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| ADORA2B | adenosine A2b receptor |
| AIM1 | absent in melanoma 1 |
| ALB | albumin |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANXA1 | annexin A1 |
| AREG | amphiregulin |
| ARG2 | arginase 2 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCND2 | cyclin D2 |
| CD44 | CD44 molecule (Indian blood group) |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CLEC5A | C-type lectin domain family 5, member A |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EPAS1 | endothelial PAS domain protein 1 |
| EREG | epiregulin |
| FAM129A | family with sequence similarity 129, member A |
| FAM69A | family with sequence similarity 69, member A |
| FHL1 | four and a half LIM domains 1 |
| FN1 | fibronectin 1 |
| FOSL1 | FOS-like antigen 1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLIPR1 | GLI pathogenesis-related 1 |
| HOPX | HOP homeobox |
| HPCAL1 | hippocalcin-like 1 |
| IER3 | immediate early response 3 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGHM | immunoglobulin heavy constant mu |
| IPO13 | importin 13 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITGB5 | integrin, beta 5 |
| JAG1 | jagged 1 |
| JUN | jun proto-oncogene |
| LDHB | lactate dehydrogenase B |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MT1X | metallothionein 1X |
| NEB | nebulin |
| NPTX2 | neuronal pentraxin II |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTS | neurotensin |
| P3H2 | prolyl 3-hydroxylase 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PEA15 | phosphoprotein enriched in astrocytes 15 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLN | phospholamban |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RAI14 | retinoic acid induced 14 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGCC | regulator of cell cycle |
| RND3 | Rho family GTPase 3 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPRR3 | small proline-rich protein 3 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TPM2 | tropomyosin 2 (beta) |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM2 | tripartite motif containing 2 |
| TUBB2A | tubulin, beta 2A class IIa |
| VEGFA | vascular endothelial growth factor A |
| WT1 | Wilms tumor 1 |
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ARMT1 | acidic residue methyltransferase 1 |
| B3GNT1 | |
| BST2 | bone marrow stromal cell antigen 2 |
| CA12 | carbonic anhydrase XII |
| CDC42 | cell division cycle 42 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CDK4 | cyclin-dependent kinase 4 |
| CIRBP | cold inducible RNA binding protein |
| CLU | clusterin |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DLD | dihydrolipoamide dehydrogenase |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EBP | emopamil binding protein (sterol isomerase) |
| EED | embryonic ectoderm development |
| EIF5A | eukaryotic translation initiation factor 5A |
| ESR1 | estrogen receptor 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAM63A | family with sequence similarity 63, member A |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GATA3 | GATA binding protein 3 |
| GCH1 | GTP cyclohydrolase 1 |
| GMFB | glia maturation factor, beta |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HLTF | helicase-like transcription factor |
| HOXC6 | homeobox C6 |
| HSPA1A | heat shock 70kDa protein 1A |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRX5 | iroquois homeobox 5 |
| KRT19 | keratin 19, type I |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MARCKSL1 | MARCKS-like 1 |
| MBP | myelin basic protein |
| MRPS30 | mitochondrial ribosomal protein S30 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MUC1 | mucin 1, cell surface associated |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NET1 | neuroepithelial cell transforming 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NRCAM | neuronal cell adhesion molecule |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PRKCD | protein kinase C, delta |
| PTGES | prostaglandin E synthase |
| QDPR | quinoid dihydropteridine reductase |
| RBBP4 | retinoblastoma binding protein 4 |
| RPS27L | ribosomal protein S27-like |
| SEPHS2 | selenophosphate synthetase 2 |
| SET | SET nuclear proto-oncogene |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STC2 | stanniocalcin 2 |
| TFF3 | trefoil factor 3 (intestinal) |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPBG | trophoblast glycoprotein |
| TPD52L1 | tumor protein D52-like 1 |
| TYMS | thymidylate synthetase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBL3 | ubiquitin-like 3 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| XBP1 | X-box binding protein 1 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZWINT | ZW10 interacting kinetochore protein |
