Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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66 genes differentially expressed following the BRD-K78431006_crizotinib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CCND2 | cyclin D2 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CRLF1 | cytokine receptor-like factor 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DMXL2 | Dmx-like 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
FAS | Fas cell surface death receptor |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
GRWD1 | glutamate-rich WD repeat containing 1 |
GSTT1 | glutathione S-transferase theta 1 |
JCHAIN | joining chain of multimeric IgA and IgM |
KDM5D | lysine (K)-specific demethylase 5D |
KRT19 | keratin 19, type I |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
OPN3 | opsin 3 |
RBM15B | RNA binding motif protein 15B |
RHOB | ras homolog family member B |
S100P | S100 calcium binding protein P |
SMAD7 | SMAD family member 7 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPP1 | secreted phosphoprotein 1 |
TBL1X | transducin (beta)-like 1X-linked |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TPST2 | tyrosylprotein sulfotransferase 2 |
VEGFA | vascular endothelial growth factor A |
Symbol | Name |
---|---|
ANXA3 | annexin A3 |
C6ORF62 | chromosome 6 open reading frame 62 |
CCNE2 | cyclin E2 |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
COL3A1 | collagen, type III, alpha 1 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYBA | cytochrome b-245, alpha polypeptide |
EIF5 | eukaryotic translation initiation factor 5 |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FBN1 | fibrillin 1 |
FCGBP | Fc fragment of IgG binding protein |
GAL | galanin/GMAP prepropeptide |
GAS1 | growth arrest-specific 1 |
GPM6B | glycoprotein M6B |
GREM1 | gremlin 1, DAN family BMP antagonist |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HOXC6 | homeobox C6 |
HSPA2 | heat shock 70kDa protein 2 |
LPAR1 | lysophosphatidic acid receptor 1 |
MAB21L2 | mab-21-like 2 (C. elegans) |
MAPT | microtubule-associated protein tau |
MATN2 | matrilin 2 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PLAC8 | placenta-specific 8 |
PLP1 | proteolipid protein 1 |
RGS5 | regulator of G-protein signaling 5 |
RPS11 | ribosomal protein S11 |
SYT1 | synaptotagmin I |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TUBB2B | tubulin, beta 2B class IIb |
XIST | X inactive specific transcript (non-protein coding) |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |