| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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112 genes differentially expressed following the BRD-K78431006_crizotinib_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BIRC2 | baculoviral IAP repeat containing 2 |
| CD24 | CD24 molecule |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLEC2B | C-type lectin domain family 2, member B |
| CLU | clusterin |
| CP | ceruloplasmin (ferroxidase) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EXOSC4 | exosome component 4 |
| FAM60A | family with sequence similarity 60, member A |
| FBLN1 | fibulin 1 |
| FBN2 | fibrillin 2 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GLA | galactosidase, alpha |
| GPX3 | glutathione peroxidase 3 |
| HIST1H2BD | histone cluster 1, H2bd |
| ICAM1 | intercellular adhesion molecule 1 |
| INSM1 | insulinoma-associated 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KIF14 | kinesin family member 14 |
| KRT18 | keratin 18, type I |
| KRT5 | keratin 5, type II |
| MEIS2 | Meis homeobox 2 |
| MMP10 | matrix metallopeptidase 10 |
| MMP7 | matrix metallopeptidase 7 |
| NOV | nephroblastoma overexpressed |
| OLFM4 | olfactomedin 4 |
| OPN3 | opsin 3 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDGFD | platelet derived growth factor D |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEG10 | paternally expressed 10 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PLAU | plasminogen activator, urokinase |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PRAME | preferentially expressed antigen in melanoma |
| PROM1 | prominin 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS2 | thrombospondin 2 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
| TKTL1 | transketolase-like 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS3 | tensin 3 |
| TPBG | trophoblast glycoprotein |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIM29 | tripartite motif containing 29 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| BRCA1 | breast cancer 1, early onset |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHL1 | cell adhesion molecule L1-like |
| CKB | creatine kinase, brain |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| HOPX | HOP homeobox |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI44L | interferon-induced protein 44-like |
| IFRD2 | interferon-related developmental regulator 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KIAA1033 | KIAA1033 |
| LAGE3 | L antigen family, member 3 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAOA | monoamine oxidase A |
| MAT2A | methionine adenosyltransferase II, alpha |
| MME | membrane metallo-endopeptidase |
| MX1 | MX dynamin-like GTPase 1 |
| NELL2 | NEL-like 2 (chicken) |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| ODC1 | ornithine decarboxylase 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSPH | phosphoserine phosphatase |
| PWP1 | PWP1 homolog (S. cerevisiae) |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNASET2 | ribonuclease T2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STMN2 | stathmin 2 |
| TSPAN8 | tetraspanin 8 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
| ZIC1 | Zic family member 1 |
