| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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91 genes differentially expressed following the BRD-K78431006_crizotinib_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| BEX1 | brain expressed, X-linked 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CADM1 | cell adhesion molecule 1 |
| CCNE2 | cyclin E2 |
| CD14 | CD14 molecule |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHI3L2 | chitinase 3-like 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DMD | dystrophin |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| FGG | fibrinogen gamma chain |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLUL | glutamate-ammonia ligase |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| HK2 | hexokinase 2 |
| HMGA2 | high mobility group AT-hook 2 |
| HOPX | HOP homeobox |
| ITM2A | integral membrane protein 2A |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| MTA1 | metastasis associated 1 |
| MYLK | myosin light chain kinase |
| NDRG1 | N-myc downstream regulated 1 |
| NEFL | neurofilament, light polypeptide |
| NEFM | neurofilament, medium polypeptide |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NRN1 | neuritin 1 |
| OLFM1 | olfactomedin 1 |
| PEG3 | paternally expressed 3 |
| PFKP | phosphofructokinase, platelet |
| PTN | pleiotrophin |
| RAD51C | RAD51 paralog C |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| Symbol | Name |
|---|---|
| AEBP1 | AE binding protein 1 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ASPN | asporin |
| CFH | complement factor H |
| CHN1 | chimerin 1 |
| COMP | cartilage oligomeric matrix protein |
| CTBP2 | C-terminal binding protein 2 |
| CTGF | connective tissue growth factor |
| DPT | dermatopontin |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GATA2 | GATA binding protein 2 |
| GOLT1B | golgi transport 1B |
| GSTT1 | glutathione S-transferase theta 1 |
| HBB | hemoglobin, beta |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFITM1 | interferon induced transmembrane protein 1 |
| INHBA | inhibin, beta A |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| MECOM | MDS1 and EVI1 complex locus |
| MFAP2 | microfibrillar-associated protein 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| MYLIP | myosin regulatory light chain interacting protein |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NNMT | nicotinamide N-methyltransferase |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PRKCD | protein kinase C, delta |
| PROM1 | prominin 1 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RUFY2 | RUN and FYVE domain containing 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SPP1 | secreted phosphoprotein 1 |
| STXBP2 | syntaxin binding protein 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSPAN13 | tetraspanin 13 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VAMP8 | vesicle-associated membrane protein 8 |
| VWA5A | von Willebrand factor A domain containing 5A |
| XIST | X inactive specific transcript (non-protein coding) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
