| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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66 genes differentially expressed following the BRD-K78599730_manumycin A_MCF7_24.0_h_9.08_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD24 | CD24 molecule |
| CTSL | cathepsin L |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| HMOX1 | heme oxygenase 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| JAG1 | jagged 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SNAI2 | snail family zinc finger 2 |
| SRGN | serglycin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TGM2 | transglutaminase 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TXNRD1 | thioredoxin reductase 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKB | aurora kinase B |
| BARD1 | BRCA1 associated RING domain 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CENPA | centromere protein A |
| CENPU | centromere protein U |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DCK | deoxycytidine kinase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| HELLS | helicase, lymphoid-specific |
| HOXC6 | homeobox C6 |
| KIF20A | kinesin family member 20A |
| KIF2C | kinesin family member 2C |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM7 | minichromosome maintenance complex component 7 |
| MKI67 | marker of proliferation Ki-67 |
| MUC1 | mucin 1, cell surface associated |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PBK | PDZ binding kinase |
| PLK1 | polo-like kinase 1 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RRM2 | ribonucleotide reductase M2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| STMN1 | stathmin 1 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TTK | TTK protein kinase |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
