| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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168 genes differentially expressed following the BRD-K78599730_manumycin A_RKO_6.0_h_9.07999992371_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACOT13 | acyl-CoA thioesterase 13 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AK5 | adenylate kinase 5 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BAG3 | BCL2-associated athanogene 3 |
| BEX1 | brain expressed, X-linked 1 |
| BEX4 | brain expressed, X-linked 4 |
| BMP4 | bone morphogenetic protein 4 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CADM1 | cell adhesion molecule 1 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CD1E | CD1e molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CD52 | CD52 molecule |
| CD9 | CD9 molecule |
| CEP57 | centrosomal protein 57kDa |
| CHMP4A | charged multivesicular body protein 4A |
| COL4A5 | collagen, type IV, alpha 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL5A2 | collagen, type V, alpha 2 |
| COLEC12 | collectin sub-family member 12 |
| CPE | carboxypeptidase E |
| CREM | cAMP responsive element modulator |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EFHD1 | EF-hand domain family, member D1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPAS1 | endothelial PAS domain protein 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FDX1 | ferredoxin 1 |
| FHL1 | four and a half LIM domains 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FN1 | fibronectin 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLUL | glutamate-ammonia ligase |
| GPNMB | glycoprotein (transmembrane) nmb |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHM | immunoglobulin heavy constant mu |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP12 | matrix metallopeptidase 12 |
| MPO | myeloperoxidase |
| NEBL | nebulette |
| NPTX2 | neuronal pentraxin II |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDLIM3 | PDZ and LIM domain 3 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCL1 | phospholipase C-like 1 |
| POSTN | periostin, osteoblast specific factor |
| PRKCI | protein kinase C, iota |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGCC | regulator of cell cycle |
| RGS5 | regulator of G-protein signaling 5 |
| S100A8 | S100 calcium binding protein A8 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERINC3 | serine incorporator 3 |
| SERINC5 | serine incorporator 5 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SULF1 | sulfatase 1 |
| TBX3 | T-box 3 |
| TCF4 | transcription factor 4 |
| THBS1 | thrombospondin 1 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TPD52 | tumor protein D52 |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TRPS1 | trichorhinophalangeal syndrome I |
| UGP2 | UDP-glucose pyrophosphorylase 2 |
| VCAN | versican |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ACLY | ATP citrate lyase |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| BIN1 | bridging integrator 1 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CD47 | CD47 molecule |
| CDC42 | cell division cycle 42 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CSTA | cystatin A (stefin A) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| EDF1 | endothelial differentiation-related factor 1 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FLNA | filamin A, alpha |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GOLM1 | golgi membrane protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSTP1 | glutathione S-transferase pi 1 |
| IER3 | immediate early response 3 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ITGB5 | integrin, beta 5 |
| KAZN | kazrin, periplakin interacting protein |
| KIF2C | kinesin family member 2C |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT10 | keratin 10, type I |
| LBR | lamin B receptor |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIMA1 | LIM domain and actin binding 1 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGLL | monoglyceride lipase |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MTA1 | metastasis associated 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NUP62 | nucleoporin 62kDa |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PLAC8 | placenta-specific 8 |
| PODXL | podocalyxin-like |
| PRDX2 | peroxiredoxin 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein |
| PYCARD | PYD and CARD domain containing |
| RPL36 | ribosomal protein L36 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP1B | ribosomal RNA processing 1B |
| SCAND1 | SCAN domain containing 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 |
| SORD | sorbitol dehydrogenase |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPAN8 | tetraspanin 8 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VAT1 | vesicle amine transport 1 |
| VGLL4 | vestigial-like family member 4 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 |
