BRD-K79090631_CGP-60474_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

829 genes differentially expressed following the BRD-K79090631_CGP-60474_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACP5 acid phosphatase 5, tartrate resistant
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY1 adenylate cyclase 1 (brain)
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOR1 adiponectin receptor 1
ADIRF adipogenesis regulatory factor
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AHCY adenosylhomocysteinase
AIDA axin interactor, dorsalization associated
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALOX5 arachidonate 5-lipoxygenase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPT1 angiopoietin 1
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
ANXA4 annexin A4
ANXA9 annexin A9
AOC3 amine oxidase, copper containing 3
AOX1 aldehyde oxidase 1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
AQP1 aquaporin 1 (Colton blood group)
ARL3 ADP-ribosylation factor-like 3
ATF3 activating transcription factor 3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAG1 BCL2-associated athanogene
BANK1 B-cell scaffold protein with ankyrin repeats 1
BEX1 brain expressed, X-linked 1
BLNK B-cell linker
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BSG basigin (Ok blood group)
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C7 complement component 7
C9ORF16 chromosome 9 open reading frame 16
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CALU calumenin
CAPN1 calpain 1, (mu/I) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCDC176 coiled-coil domain containing 176
CCL19 chemokine (C-C motif) ligand 19
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CCL8 chemokine (C-C motif) ligand 8
CD200 CD200 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD4 CD4 molecule
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD52 CD52 molecule
CD59 CD59 molecule, complement regulatory protein
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CECR1 cat eye syndrome chromosome region, candidate 1
CERS6 ceramide synthase 6
CES1 carboxylesterase 1
CETN2 centrin, EF-hand protein, 2
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFI complement factor I
CHMP1B charged multivesicular body protein 1B
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKAP4 cytoskeleton-associated protein 4
CKLF chemokine-like factor
CLCA1 chloride channel accessory 1
CLCA4 chloride channel accessory 4
CLCN3 chloride channel, voltage-sensitive 3
CLGN calmegin
CLIC2 chloride intracellular channel 2
CLIC4 chloride intracellular channel 4
CLIC5 chloride intracellular channel 5
CLU clusterin
CNOT4 CCR4-NOT transcription complex, subunit 4
COL11A1 collagen, type XI, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COL6A3 collagen, type VI, alpha 3
COLEC12 collectin sub-family member 12
COPZ2 coatomer protein complex, subunit zeta 2
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CPM carboxypeptidase M
CPVL carboxypeptidase, vitellogenic-like
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRTAP cartilage associated protein
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSRP2 cysteine and glycine-rich protein 2
CTBS chitobiase, di-N-acetyl-
CTGF connective tissue growth factor
CTSB cathepsin B
CTSD cathepsin D
CTSO cathepsin O
CTSS cathepsin S
CTTN cortactin
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYBA cytochrome b-245, alpha polypeptide
CYBRD1 cytochrome b reductase 1
CYCS cytochrome c, somatic
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAZAP2 DAZ associated protein 2
DCTD dCMP deaminase
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFB1 defensin, beta 1
DICER1 dicer 1, ribonuclease type III
DIO1 deiodinase, iodothyronine, type I
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1 dynamin 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DSE dermatan sulfate epimerase
DSP desmoplakin
DST dystonin
DUSP1 dual specificity phosphatase 1
DYNLT3 dynein, light chain, Tctex-type 3
ECM1 extracellular matrix protein 1
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
EGR3 early growth response 3
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENO2 enolase 2 (gamma, neuronal)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPCAM epithelial cell adhesion molecule
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
EXPH5 exophilin 5
EYA1 EYA transcriptional coactivator and phosphatase 1
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F8 coagulation factor VIII, procoagulant component
FAM129A family with sequence similarity 129, member A
FAM134B family with sequence similarity 134, member B
FAM149A family with sequence similarity 149, member A
FAM162A family with sequence similarity 162, member A
FAM20B family with sequence similarity 20, member B
FAS Fas cell surface death receptor
FBLN1 fibulin 1
FBN1 fibrillin 1
FECH ferrochelatase
FGA fibrinogen alpha chain
FGF13 fibroblast growth factor 13
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXF1 forkhead box F1
FPR3 formyl peptide receptor 3
FRY furry homolog (Drosophila)
FRZB frizzled-related protein
FUCA1 fucosidase, alpha-L- 1, tissue
G6PD glucose-6-phosphate dehydrogenase
GAA glucosidase, alpha; acid
GADD45B growth arrest and DNA-damage-inducible, beta
GAS6 growth arrest-specific 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GHR growth hormone receptor
GLUD1 glutamate dehydrogenase 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNS glucosamine (N-acetyl)-6-sulfatase
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
GRB14 growth factor receptor-bound protein 14
GRN granulin
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
GSTM3 glutathione S-transferase mu 3 (brain)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUK1 guanylate kinase 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HBE1 hemoglobin, epsilon 1
HCAR3 hydroxycarboxylic acid receptor 3
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H1C histone cluster 1, H1c
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HMGN4 high mobility group nucleosomal binding domain 4
HMGN5 high mobility group nucleosome binding domain 5
HRASLS HRAS-like suppressor
HSPB8 heat shock 22kDa protein 8
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IDS iduronate 2-sulfatase
IFI30 interferon, gamma-inducible protein 30
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL13RA2 interleukin 13 receptor, alpha 2
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL6ST interleukin 6 signal transducer
INHBA inhibin, beta A
IRX5 iroquois homeobox 5
ISCA1 iron-sulfur cluster assembly 1
ISYNA1 inositol-3-phosphate synthase 1
ITGB5 integrin, beta 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITM2A integral membrane protein 2A
ITM2C integral membrane protein 2C
JUND jun D proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK3 potassium channel, two pore domain subfamily K, member 3
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KLF9 Kruppel-like factor 9
KRT4 keratin 4, type II
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LDOC1 leucine zipper, down-regulated in cancer 1
LEPR leptin receptor
LITAF lipopolysaccharide-induced TNF factor
LOX lysyl oxidase
LPAR2 lysophosphatidic acid receptor 2
LRRC17 leucine rich repeat containing 17
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP1 latent transforming growth factor beta binding protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAGT1 magnesium transporter 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MATN2 matrilin 2
MBNL2 muscleblind-like splicing regulator 2
MCUR1 mitochondrial calcium uniporter regulator 1
MDFIC MyoD family inhibitor domain containing
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MEOX2 mesenchyme homeobox 2
METRN meteorin, glial cell differentiation regulator
METTL7A methyltransferase like 7A
MFAP3L microfibrillar-associated protein 3-like
MLF2 myeloid leukemia factor 2
MME membrane metallo-endopeptidase
MMP19 matrix metallopeptidase 19
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MT1E metallothionein 1E
MUC16 mucin 16, cell surface associated
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MXRA7 matrix-remodelling associated 7
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDFIP1 Nedd4 family interacting protein 1
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NID2 nidogen 2 (osteonidogen)
NLRP2 NLR family, pyrin domain containing 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
NMU neuromedin U
NOTCH3 notch 3
NPR1 natriuretic peptide receptor 1
NPTX2 neuronal pentraxin II
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5DC2 5'-nucleotidase domain containing 2
NTS neurotensin
NUCB1 nucleobindin 1
NUPR1 nuclear protein, transcriptional regulator, 1
OAT ornithine aminotransferase
OLFM4 olfactomedin 4
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORM1 orosomucoid 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PALLD palladin, cytoskeletal associated protein
PAMR1 peptidase domain containing associated with muscle regeneration 1
PCOLCE procollagen C-endopeptidase enhancer
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PDIA3 protein disulfide isomerase family A, member 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZK1 PDZ domain containing 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PERP PERP, TP53 apoptosis effector
PHACTR2 phosphatase and actin regulator 2
PHKB phosphorylase kinase, beta
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PILRB paired immunoglobin-like type 2 receptor beta
PLAGL1 pleiomorphic adenoma gene-like 1
PLD3 phospholipase D family, member 3
PLS1 plastin 1
PLS3 plastin 3
PLVAP plasmalemma vesicle associated protein
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPT1 palmitoyl-protein thioesterase 1
PRAF2 PRA1 domain family, member 2
PRAME preferentially expressed antigen in melanoma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCI protein kinase C, iota
PROS1 protein S (alpha)
PRPF4 pre-mRNA processing factor 4
PRR7 proline rich 7 (synaptic)
PSENEN presenilin enhancer gamma secretase subunit
PSPH phosphoserine phosphatase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRC protein tyrosine phosphatase, receptor type, C
QDPR quinoid dihydropteridine reductase
QPCT glutaminyl-peptide cyclotransferase
R3HDM4 R3H domain containing 4
RAB31 RAB31, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAI2 retinoic acid induced 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBKS ribokinase
RBP1 retinol binding protein 1, cellular
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
REG3A regenerating islet-derived 3 alpha
RELN reelin
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
RGS5 regulator of G-protein signaling 5
RHOC ras homolog family member C
RHOQ ras homolog family member Q
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF130 ring finger protein 130
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS5 ribosomal protein S5
RRAGD Ras-related GTP binding D
RSAD2 radical S-adenosyl methionine domain containing 2
RTN1 reticulon 1
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCD5 stearoyl-CoA desaturase 5
SCG5 secretogranin V
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCPEP1 serine carboxypeptidase 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK1 salt-inducible kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLIT2 slit homolog 2 (Drosophila)
SNX10 sorting nexin 10
SORD sorbitol dehydrogenase
SPARCL1 SPARC-like 1 (hevin)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPP1 secreted phosphoprotein 1
SRPR signal recognition particle receptor (docking protein)
SSBP2 single-stranded DNA binding protein 2
SSR4 signal sequence receptor, delta
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STC1 stanniocalcin 1
SULF1 sulfatase 1
SYNGR3 synaptogyrin 3
SYT1 synaptotagmin I
TAGLN2 transgelin 2
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TBX2 T-box 2
TCF4 transcription factor 4
TCTA T-cell leukemia translocation altered
TCTN1 tectonic family member 1
TDO2 tryptophan 2,3-dioxygenase
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM106B transmembrane protein 106B
TMEM14B transmembrane protein 14B
TMEM176A transmembrane protein 176A
TMEM259 transmembrane protein 259
TMEM38B transmembrane protein 38B
TMEM47 transmembrane protein 47
TMOD1 tropomodulin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52 tumor protein D52
TPGS2 tubulin polyglutamylase complex subunit 2
TPM2 tropomyosin 2 (beta)
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TRAK2 trafficking protein, kinesin binding 2
TRBC1 T cell receptor beta constant 1
TSKU tsukushi, small leucine rich proteoglycan
TSPAN13 tetraspanin 13
TSPAN7 tetraspanin 7
TSTA3 tissue specific transplantation antigen P35B
TTC3 tetratricopeptide repeat domain 3
TUSC3 tumor suppressor candidate 3
TWF1 twinfilin actin binding protein 1
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
UBE2B ubiquitin-conjugating enzyme E2B
UBE2M ubiquitin-conjugating enzyme E2M
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
VAMP7 vesicle-associated membrane protein 7
VARS valyl-tRNA synthetase
VAV3 vav 3 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor
WASF3 WAS protein family, member 3
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A
WSB1 WD repeat and SOCS box containing 1
XAF1 XIAP associated factor 1
XIST X inactive specific transcript (non-protein coding)
XYLT1 xylosyltransferase I
YIPF5 Yip1 domain family, member 5
ZBED2 zinc finger, BED-type containing 2
ZNF148 zinc finger protein 148
ZNF318 zinc finger protein 318
ZNF331 zinc finger protein 331
ZNF467 zinc finger protein 467
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACBD3 acyl-CoA binding domain containing 3
ACTA1 actin, alpha 1, skeletal muscle
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
AHNAK2 AHNAK nucleoprotein 2
AKAP1 A kinase (PRKA) anchor protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMD1 adenosylmethionine decarboxylase 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARF6 ADP-ribosylation factor 6
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMCX6 armadillo repeat containing, X-linked 6
ATMIN ATM interactor
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BIN1 bridging integrator 1
BLCAP bladder cancer associated protein
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF169 chromosome 14 open reading frame 169
CA12 carbonic anhydrase XII
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CANT1 calcium activated nucleotidase 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNG2 cyclin G2
CD164 CD164 molecule, sialomucin
CD24 CD24 molecule
CD58 CD58 molecule
CDC123 cell division cycle 123
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COG2 component of oligomeric golgi complex 2
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRNKL1 crooked neck pre-mRNA splicing factor 1
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTBP2 C-terminal binding protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
ECD ecdysoneless homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
ELF5 E74-like factor 5 (ets domain transcription factor)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA3 EPH receptor A3
EXOSC4 exosome component 4
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FEN1 flap structure-specific endonuclease 1
FERMT1 fermitin family member 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPATCH8 G patch domain containing 8
GPX2 glutathione peroxidase 2
GSPT2 G1 to S phase transition 2
GTPBP8 GTP-binding protein 8 (putative)
GYG1 glycogenin 1
H2AFX H2A histone family, member X
HES1 hes family bHLH transcription factor 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOPX HOP homeobox
HOXA10 homeobox A10
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDI1 isopentenyl-diphosphate delta isomerase 1
IGL immunoglobulin lambda locus
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
IRS2 insulin receptor substrate 2
ITPKB inositol-trisphosphate 3-kinase B
JMJD6 jumonji domain containing 6
KANK1 KN motif and ankyrin repeat domains 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM3A lysine (K)-specific demethylase 3A
KEAP1 kelch-like ECH-associated protein 1
KIAA0101 KIAA0101
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
KRT81 keratin 81, type II
LBR lamin B receptor
LDLR low density lipoprotein receptor
LIPG lipase, endothelial
LTF lactotransferrin
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK6 mitogen-activated protein kinase 6
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MAT2A methionine adenosyltransferase II, alpha
MAVS mitochondrial antiviral signaling protein
MED17 mediator complex subunit 17
MELK maternal embryonic leucine zipper kinase
METTL3 methyltransferase like 3
MGLL monoglyceride lipase
MKKS McKusick-Kaufman syndrome
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPRIP myosin phosphatase Rho interacting protein
MRPS30 mitochondrial ribosomal protein S30
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTERF3 mitochondrial transcription termination factor 3
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBPC1 myosin binding protein C, slow type
NES nestin
NGDN neuroguidin, EIF4E binding protein
NMI N-myc (and STAT) interactor
NOL11 nucleolar protein 11
NOP56 NOP56 ribonucleoprotein
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
NSFL1C NSFL1 (p97) cofactor (p47)
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
NXT1 nuclear transport factor 2-like export factor 1
OXA1L oxidase (cytochrome c) assembly 1-like
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PANK2 pantothenate kinase 2
PARP2 poly (ADP-ribose) polymerase 2
PCDH9 protocadherin 9
PCNA proliferating cell nuclear antigen
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PI3 peptidase inhibitor 3, skin-derived
PKP1 plakophilin 1
PLAU plasminogen activator, urokinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PMM2 phosphomannomutase 2
PMP22 peripheral myelin protein 22
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POU2AF1 POU class 2 associating factor 1
PPARG peroxisome proliferator-activated receptor gamma
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKCDBP protein kinase C, delta binding protein
PRPF4B pre-mRNA processing factor 4B
PSCA prostate stem cell antigen
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PUF60 poly-U binding splicing factor 60KDa
RAB14 RAB14, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAD51C RAD51 paralog C
RAE1 ribonucleic acid export 1
RAN RAN, member RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBM34 RNA binding motif protein 34
RBM39 RNA binding motif protein 39
RDX radixin
RFTN1 raftlin, lipid raft linker 1
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
RNMT RNA (guanine-7-) methyltransferase
RNPS1 RNA binding protein S1, serine-rich domain
RPL10 ribosomal protein L10
RPL36AL ribosomal protein L36a-like
RPS11 ribosomal protein S11
RREB1 ras responsive element binding protein 1
RRM2 ribonucleotide reductase M2
S100A10 S100 calcium binding protein A10
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SCGB2A2 secretoglobin, family 2A, member 2
SDC4 syndecan 4
SEC23B Sec23 homolog B (S. cerevisiae)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC35F2 solute carrier family 35, member F2
SLC38A2 solute carrier family 38, member 2
SLC43A3 solute carrier family 43, member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLN sarcolipin
SMAD1 SMAD family member 1
SMC4 structural maintenance of chromosomes 4
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNX5 sorting nexin 5
SOBP sine oculis binding protein homolog (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR1A small proline-rich protein 1A
SPRY2 sprouty homolog 2 (Drosophila)
SRGN serglycin
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACC2 transforming, acidic coiled-coil containing protein 2
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TMEM97 transmembrane protein 97
TMPO thymopoietin
TMPRSS4 transmembrane protease, serine 4
TMX4 thioredoxin-related transmembrane protein 4
TNPO1 transportin 1
TOB1 transducer of ERBB2, 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRAPPC3 trafficking protein particle complex 3
TSC22D2 TSC22 domain family, member 2
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
TTN titin
TUBA4A tubulin, alpha 4a
TUBB4B tubulin, beta 4B class IVb
TXLNA taxilin alpha
TXNDC9 thioredoxin domain containing 9
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UPP1 uridine phosphorylase 1
USP1 ubiquitin specific peptidase 1
USP22 ubiquitin specific peptidase 22
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VCAN versican
VGLL4 vestigial-like family member 4
WDR6 WD repeat domain 6
WEE1 WEE1 G2 checkpoint kinase
YBX3 Y box binding protein 3
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZBED5 zinc finger, BED-type containing 5
ZDHHC7 zinc finger, DHHC-type containing 7
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYM2 zinc finger, MYM-type 2
ZNF185 zinc finger protein 185 (LIM domain)
ZNF266 zinc finger protein 266
Funding