| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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207 genes differentially expressed following the BRD-K79090631_CGP-60474_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADD3 | adducin 3 (gamma) |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANPEP | alanyl (membrane) aminopeptidase |
| AOX1 | aldehyde oxidase 1 |
| ATP13A3 | ATPase type 13A3 |
| BID | BH3 interacting domain death agonist |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CEP350 | centrosomal protein 350kDa |
| CEP70 | centrosomal protein 70kDa |
| CES2 | carboxylesterase 2 |
| COL1A2 | collagen, type I, alpha 2 |
| COL4A5 | collagen, type IV, alpha 5 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CTSB | cathepsin B |
| CTSV | cathepsin V |
| CYBRD1 | cytochrome b reductase 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DLX2 | distal-less homeobox 2 |
| DST | dystonin |
| EGR1 | early growth response 1 |
| EPHA3 | EPH receptor A3 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| FAM134B | family with sequence similarity 134, member B |
| FAM8A1 | family with sequence similarity 8, member A1 |
| FHL1 | four and a half LIM domains 1 |
| FKBP5 | FK506 binding protein 5 |
| FNDC3B | fibronectin type III domain containing 3B |
| FOXC1 | forkhead box C1 |
| FRY | furry homolog (Drosophila) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GOLIM4 | golgi integral membrane protein 4 |
| GPC3 | glypican 3 |
| GPX3 | glutathione peroxidase 3 |
| GRB14 | growth factor receptor-bound protein 14 |
| HMGN4 | high mobility group nucleosomal binding domain 4 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL2RG | interleukin 2 receptor, gamma |
| IQCK | IQ motif containing K |
| IRS1 | insulin receptor substrate 1 |
| ITM2A | integral membrane protein 2A |
| JUN | jun proto-oncogene |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KLF9 | Kruppel-like factor 9 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LOX | lysyl oxidase |
| LRRC17 | leucine rich repeat containing 17 |
| LTF | lactotransferrin |
| MAOA | monoamine oxidase A |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MATN2 | matrilin 2 |
| MCL1 | myeloid cell leukemia 1 |
| MGP | matrix Gla protein |
| MT1F | metallothionein 1F |
| MXI1 | MAX interactor 1, dimerization protein |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OSMR | oncostatin M receptor |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PAX8 | paired box 8 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLAT | plasminogen activator, tissue |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RBP1 | retinol binding protein 1, cellular |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMC1A | structural maintenance of chromosomes 1A |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SRPR | signal recognition particle receptor (docking protein) |
| STC1 | stanniocalcin 1 |
| TGFA | transforming growth factor, alpha |
| THBS4 | thrombospondin 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNC | tenascin C |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TSPAN1 | tetraspanin 1 |
| TTC3 | tetratricopeptide repeat domain 3 |
| TXNIP | thioredoxin interacting protein |
| WFDC2 | WAP four-disulfide core domain 2 |
| WWTR1 | WW domain containing transcription regulator 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZIC1 | Zic family member 1 |
| ZNF91 | zinc finger protein 91 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| ALCAM | activated leukocyte cell adhesion molecule |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CASC3 | cancer susceptibility candidate 3 |
| CCND1 | cyclin D1 |
| CD24 | CD24 molecule |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDC42 | cell division cycle 42 |
| CDK1 | cyclin-dependent kinase 1 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CLU | clusterin |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DCK | deoxycytidine kinase |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHCR24 | 24-dehydrocholesterol reductase |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF4A1 | eukaryotic translation initiation factor 4A1 |
| ELOVL1 | ELOVL fatty acid elongase 1 |
| ENO1 | enolase 1, (alpha) |
| EXT1 | exostosin glycosyltransferase 1 |
| FASN | fatty acid synthase |
| FGFR2 | fibroblast growth factor receptor 2 |
| GID8 | GID complex subunit 8 |
| H2AFZ | H2A histone family, member Z |
| HN1 | hematological and neurological expressed 1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| ILF2 | interleukin enhancer binding factor 2 |
| INHBB | inhibin, beta B |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT14 | keratin 14, type I |
| KRT19 | keratin 19, type I |
| KRT23 | keratin 23, type I |
| KRT7 | keratin 7, type II |
| MAGEA3 | melanoma antigen family A3 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MED24 | mediator complex subunit 24 |
| MELK | maternal embryonic leucine zipper kinase |
| MLPH | melanophilin |
| MMP11 | matrix metallopeptidase 11 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NET1 | neuroepithelial cell transforming 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| OPN3 | opsin 3 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCNA | proliferating cell nuclear antigen |
| PFDN4 | prefoldin subunit 4 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PON2 | paraoxonase 2 |
| PSAP | prosaposin |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAE1 | ribonucleic acid export 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| RPL27A | ribosomal protein L27a |
| RPL38 | ribosomal protein L38 |
| RPN2 | ribophorin II |
| RRBP1 | ribosome binding protein 1 |
| RRM2 | ribonucleotide reductase M2 |
| SCAND1 | SCAN domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC1 | syndecan 1 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E |
| STAU1 | staufen double-stranded RNA binding protein 1 |
| TAGLN2 | transgelin 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPAN13 | tetraspanin 13 |
| TXLNA | taxilin alpha |
| TXNRD1 | thioredoxin reductase 1 |
| TYMS | thymidylate synthetase |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UBE3C | ubiquitin protein ligase E3C |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| XBP1 | X-box binding protein 1 |
| YBX3 | Y box binding protein 3 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
| ZNF217 | zinc finger protein 217 |
