BRD-K79131256_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K79131256_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANOS1 anosmin 1
BTG3 BTG family, member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC86 coiled-coil domain containing 86
CCNA1 cyclin A1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKB creatine kinase, brain
CPE carboxypeptidase E
CTSS cathepsin S
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1 eukaryotic translation initiation factor 1
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FERMT2 fermitin family member 2
FHL1 four and a half LIM domains 1
FHL2 four and a half LIM domains 2
GADD45B growth arrest and DNA-damage-inducible, beta
GAS6 growth arrest-specific 6
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KLF6 Kruppel-like factor 6
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MT1F metallothionein 1F
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1B myosin IB
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PCP4 Purkinje cell protein 4
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SULF1 sulfatase 1

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BAMBI BMP and activin membrane-bound inhibitor
CLCN3 chloride channel, voltage-sensitive 3
COPS7A COP9 signalosome subunit 7A
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ERBB3 erb-b2 receptor tyrosine kinase 3
GDF15 growth differentiation factor 15
IER3 immediate early response 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KIAA1033 KIAA1033
LEF1 lymphoid enhancer-binding factor 1
MARCKSL1 MARCKS-like 1
MLEC malectin
NQO1 NAD(P)H dehydrogenase, quinone 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIR pirin (iron-binding nuclear protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSIP1 PC4 and SFRS1 interacting protein 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIB2 tribbles pseudokinase 2
TRIM38 tripartite motif containing 38
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa